Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | PHGDH | O43175 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.40 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967457 | 0.98 | FAAH (0.48) | FAAHPHGDHMGLLALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL21906392 | 0.98 | FAAH (0.43) | FAAHPHGDHMGLLALDH1A1ATM | |
| SCHEMBL967805 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL21906386 | 0.95 | FAAH (0.47) | FAAHPHGDHMGLLALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL28808760 | 0.95 | ALOX5 (0.40) | FAAHPHGDHMGLLALDH1A1ATM | |
| SCHEMBL967140 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL27330745 | 0.87 | — | — | |
| SCHEMBL30786309 | 0.81 | EPHX1 (0.33) | ALDH1A1ALOX5EPHX1 | |
| SCHEMBL3958681 | 0.79 | PIK3CD (0.42) | ALOX5RAB9APOLBNPC1 | |
| SCHEMBL3770001 | 0.79 | ALOX5 (0.32) | ALDH1A1ATMHPGDTSHRALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11400042-B2 | Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone | L'OREAL (FR) | 2022-08-02 | — | — | US | claimed |
| US-11298305-B2 | Compositions and methods for improving the appearance of the hair | L'OREAL (FR) | 2022-04-12 | — | — | US | claimed |
| EP-2988830-B1 | COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF | OREAL (FR) | 2021-03-17 | — | — | EP | claimed |
| EP-2916808-B1 | COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION | OREAL (FR) | 2019-06-26 | — | — | EP | claimed |
| US-20190167552-A1 | COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF THE HAIR | L'OREAL (FR) | 2019-06-06 | — | — | US | claimed |
| US-20190117551-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A COMPOSITION COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A POLYMERIC THICKENER | L'OREAL (FR) | 2019-04-25 | — | — | US | claimed |
| US-20190021983-A1 | PROCESS FOR TREATING KERATIN FIBRES, COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING UREA OR A DERIVATIVE THEREOF, A POLYOL AND AN AMINO SILICONE | L'OREAL (FR) | 2019-01-24 | — | — | US | claimed |
| EP-3393435-A1 | PROCESS FOR TREATING KERATIN FIBRES, COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING UREA OR A DERIVATIVE THEREOF, A POLYOL AND AN AMINO SILICONE | L'Oréal (FR) | 2018-10-31 | — | — | EP | claimed |
| CN-108430442-A | It include the method for handling keratin fiber using the composition comprising urea or derivatives thereof, polyalcohol and amodimethicone | 欧莱雅 | 2018-08-21 | — | — | CN | claimed |
| WO-2018000059-A1 | COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF THE HAIR | L'OREAL (FR) | 2018-01-04 | — | — | WO | claimed |
| EP-2988830-A2 | COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF | L'Oréal (FR) | 2016-03-02 | — | — | EP | claimed |
| US-20150305999-A1 | COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION | L'OREAL (FR) | 2015-10-29 | — | — | US | claimed |
| EP-2916808-A1 | COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION | L'Oréal (FR) | 2015-09-16 | — | — | EP | claimed |
| WO-2014174075-A2 | COMPOSITION FOR STRAIGHTENING KERATIN FIBRES, COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A NONIONIC, CATIONIC, AMPHOTERIC OR ANIONIC ASSOCIATIVE POLYMERIC THICKENER, PROCESS AND USE THEREOF | L'OREAL (FR) | 2014-10-30 | — | — | WO | claimed |
| EP-1661551-B1 | Method of straightening keratin fibres with heating means and a denaturant agent | ORÉAL L (FR) | 2014-08-20 | — | — | EP | claimed |
| WO-2014072658-A1 | COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION | L'OREAL (FR) | 2014-05-15 | — | — | WO | claimed |
| US-20100284954-A1 | PROCESS FOR RELAXING KERATIN FIBRES | L'OREAL (FR) | 2010-11-11 | — | — | US | claimed |
| US-20060127337-A1 | Process for relaxing keratin fibres | L'OREAL (FR) | 2006-06-15 | — | — | US | claimed |
| EP-1661551-A2 | Method of straightening keratin fibres with heating means and a denaturant agent | L'OREAL (FR) | 2006-05-31 | — | — | EP | claimed |
| CN-1080919-A | As ACAT inhibitors, new N-aryl and N-heteroaryl-ureas analog derivative | PFIZER (US) | 1994-01-19 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190021983-A1 | PROCESS FOR TREATING KERATIN FIBRES, COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING UREA OR A DERIVATIVE THEREOF, A POLYOL AND AN AMINO SILICONE | KRT18, CUTA, PUF60 | FAAH 3733/4885PHGDH 1415/4885MGLL 3672/4885 |
| US-20100284954-A1 | PROCESS FOR RELAXING KERATIN FIBRES | KRT18, TPM4, MYLK | FAAH 2924/4885PHGDH 3119/4885MGLL 4125/4885 |
| US-20190167552-A1 | COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF THE HAIR | KRT18, OAT, CKMT1A; CKMT1B | FAAH 4088/4885PHGDH 2957/4885MGLL 2829/4885 |
| US-11298305-B2 | Compositions and methods for improving the appearance of the hair | KRT18, OAT, CKMT1A; CKMT1B | FAAH 4088/4885PHGDH 2957/4885MGLL 2829/4885 |
| US-20190117551-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A COMPOSITION COMPRISING A UREA AND/OR A UREA DERIVATIVE AND A POLYMERIC THICKENER | KRT18, CUTA, MARK1 | FAAH 2814/4885PHGDH 748/4885MGLL 3748/4885 |
| US-20150305999-A1 | COMPOSITION COMPRISING A DICARBONYL DERIVATIVE AND METHOD FOR STRAIGHTENING THE HAIR USING THIS COMPOSITION | KRT18, MAPT, CUTA | FAAH 2654/4885PHGDH 1318/4885MGLL 4708/4885 |
| US-20060127337-A1 | Process for relaxing keratin fibres | KRT18, TPM4, MYLK | FAAH 2924/4885PHGDH 3119/4885MGLL 4125/4885 |
| US-11400042-B2 | Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone | KRT18, CUTA, PUF60 | FAAH 3733/4885PHGDH 1415/4885MGLL 3672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.