Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19484832 | 0.88 | HDAC8 (0.37) | MAPK1DPP4DPP8DPP7HRH3 | |
| SCHEMBL3012517 | 0.82 | PEPD (0.39) | DPP4DPP8DPP7 | |
| SCHEMBL1701540 | 0.79 | PTPN1 (0.40) | DPP4DPP8DPP7HSD17B10 | |
| SCHEMBL2207075 | 0.79 | PTPN1 (0.40) | DPP4DPP8DPP7HSD17B10 | |
| SCHEMBL706243 | 0.79 | PTPN1 (0.40) | DPP4DPP8DPP7HSD17B10 | |
| SCHEMBL193268 | 0.78 | HSD17B10 (0.41) | HSD17B10 | |
| SCHEMBL185992 | 0.78 | HSD17B10 (0.41) | HSD17B10 | |
| SCHEMBL1848946 | 0.78 | HSD17B10 (0.41) | HSD17B10 | |
| SCHEMBL3471343 | 0.76 | PDK1 (0.44) | — | |
| SCHEMBL27089331 | 0.76 | DPP4 (0.33) | DPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |