Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 8/20 | 0.33 |
| ▸ | F10 | P00742 | 10/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.32 |
| ▸ | FPR1 | P21462 | 6/20 | 0.32 |
| ▸ | FPR2 | P25090 | 6/20 | 0.32 |
| ▸ | PLG | P00747 | 2/20 | 0.30 |
| ▸ | PLAU | P00749 | 2/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | KLK1 | P06870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520638 | 0.89 | FPR1 (0.35) | F2F10PRSS1FPR1FPR2 | |
| SCHEMBL6859806 | 0.82 | F10 (0.43) | F2F10PRSS1 | |
| SCHEMBL6853311 | 0.75 | F10 (0.42) | F10 | |
| SCHEMBL6853164 | 0.74 | F10 (0.53) | F10FPR1FPR2 | |
| Hydrochloric Acid SCHEMBL27594880 | 0.72 | ANPEP (0.35) | F10FPR1FPR2 | |
| SCHEMBL6984298 | 0.67 | F10 (0.51) | F10FPR1FPR2 | |
| SCHEMBL6988835 | 0.67 | F10 (0.47) | F10FPR2 | |
| SCHEMBL27613671 | 0.65 | FPR1 (0.39) | F10FPR1FPR2 | |
| SCHEMBL6810146 | 0.64 | F10 (0.39) | F10FPR1FPR2 | |
| SCHEMBL6984447 | 0.63 | F10 (0.43) | F10FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002080853-A2 | FUSED HETEROCYCLIC INHIBITORS OF FACTOR XA | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-10-17 | — | — | WO | claimed |
| EP-4015511-A1 | OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS | CARNEGIE MELLON UNIVERSITY (US) | 2022-06-22 | — | — | EP | disclosed |
| EP-3353157-B1 | OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS | UNIV CARNEGIE MELLON (US) | 2021-11-24 | — | — | EP | disclosed |
| EP-0914206-B1 | LONG-LIVED HOMOGENOUS OXIDATION CATALYSTS | UNIV CARNEGIE MELLON (US) | 2002-12-11 | — | — | EP | disclosed |
| WO-2002080853-A2 | FUSED HETEROCYCLIC INHIBITORS OF FACTOR XA | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-10-17 | — | — | WO | disclosed |
| US-6011152-A | REACTING STOICHIOMETRIC AMOUNTS OR MORE OF AN AMINO CARBOXYLIC ACID OR A PROTECTED/ACTIVATED FOR THEREOF WITH AN ACTIVATED DERVATIVE SELECTED FROM THE GROUP CONSISTING OF OXALATES AND MALONATES IN THE PRESENCE OF A SOLVENT AND HEAT | CARNEGIE MELLON UNIVERSITY (US) | 2000-01-04 | — | — | US | disclosed |