Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 12/20 | 0.35 |
| ▸ | FPR2 | P25090 | 12/20 | 0.35 |
| ▸ | F10 | P00742 | 6/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7505078 | 0.89 | F2 (0.33) | FPR1FPR2F10F2PLG | |
| SCHEMBL6853311 | 0.84 | F10 (0.42) | F10ALOX5APFEN1 | |
| SCHEMBL6859806 | 0.76 | F10 (0.43) | F10F2PRSS1 | |
| SCHEMBL6853164 | 0.73 | F10 (0.53) | FPR1FPR2F10 | |
| SCHEMBL6858757 | 0.67 | ALOX5AP (0.36) | FPR1FPR2F10ALOX5APFEN1 | |
| SCHEMBL6984298 | 0.65 | F10 (0.51) | FPR1FPR2F10 | |
| SCHEMBL6988835 | 0.65 | F10 (0.47) | FPR2F10 | |
| SCHEMBL7450780 | 0.64 | IDO1 (0.38) | F10 | |
| SCHEMBL7554444 | 0.64 | ALOX5AP (0.48) | ALOX5APFEN1 | |
| SCHEMBL27613671 | 0.63 | FPR1 (0.39) | FPR1FPR2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002080853-A2 | FUSED HETEROCYCLIC INHIBITORS OF FACTOR XA | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-10-17 | — | — | WO | disclosed |