SCHEMBL6853311

SCHEMBL6853311

CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(N2CCC(n3ccc4ccc(C(=N)N)cc43)C2=O)c(F)c1

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 10/20 0.42
ALOX5AP P20292 10/20 0.42
FEN1 P39748 10/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6859806 0.90 F10 (0.43) F10
SCHEMBL6853164 0.86 F10 (0.53) F10
SCHEMBL7520638 0.84 FPR1 (0.35) F10ALOX5APFEN1
SCHEMBL7505078 0.75 F2 (0.33) F10
SCHEMBL6859839 0.75 F10 (0.54) F10
SCHEMBL6853111 0.72 F10 (0.52) F10
SCHEMBL6859645 0.71 F10 (0.63) F10
SCHEMBL6859980 0.69 F10 (0.53) F10
SCHEMBL6858757 0.68 ALOX5AP (0.36) F10ALOX5APFEN1
Hydrochloric Acid SCHEMBL6365725 0.68 F10 (0.54) F10ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030087909-A1 Fused heterocyclic inhibitors of factor Xa BRISTOL-MYERS SQUIBB PHARMA COMPANY 2003-05-08 US claimed
WO-2002080853-A2 FUSED HETEROCYCLIC INHIBITORS OF FACTOR XA BRISTOL-MYERS SQUIBB COMPANY (US) 2002-10-17 WO claimed
US-6790845-B2 HAVING AN ATTACHED NON-AROMATIC HETEROCYCLIC RING BRISTOL-MYERS SQUIBB PHARMA COMPANY 2004-09-14 US disclosed
US-20030087909-A1 Fused heterocyclic inhibitors of factor Xa BRISTOL-MYERS SQUIBB PHARMA COMPANY 2003-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030087909-A1 Fused heterocyclic inhibitors of factor Xa TFPI, F11, F12 F10 9/4885ALOX5AP 3796/4885FEN1 933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.