Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 13/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL747101 | 0.93 | F2 (0.39) | TACR1F2F10F7SLC13A5 | |
| SCHEMBL747162 | 0.88 | TACR1 (0.37) | TACR1SLC13A5 | |
| SCHEMBL746610 | 0.86 | TP53 (0.42) | F2F10F7SLC13A5PTGER2 | |
| SCHEMBL749644 | 0.86 | TACR1 (0.39) | TACR1SLC13A5SLC6A4PTGER4PTGER2 | |
| SCHEMBL746712 | 0.85 | F10 (0.54) | F2F10F7SLC13A5LPAR1 | |
| SCHEMBL745478 | 0.82 | TP53 (0.38) | TACR1F2F10F7SLC6A4 | |
| SCHEMBL747640 | 0.82 | TP53 (0.41) | F2F10F7SLC13A5LPAR1 | |
| SCHEMBL745468 | 0.82 | F2 (0.38) | F2F10F7SLC13A5LPAR1 | |
| SCHEMBL749589 | 0.79 | MAPT (0.48) | SLC13A5PTGER2 | |
| SCHEMBL748780 | 0.79 | TP53 (0.35) | F2F10F7SLC13A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022217-B2 | Compounds suitable as modulators of HDL | CADILA HEALTHCARE LIMITED (IN) | 2011-09-20 | — | — | US | claimed |
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | disclosed |
| US-8022217-B2 | Compounds suitable as modulators of HDL | CADILA HEALTHCARE LIMITED (IN) | 2011-09-20 | — | — | US | disclosed |