Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508801 | 0.78 | CA2 (0.39) | LMNAGAAALDH1A1 | |
| SCHEMBL3585070 | 0.76 | CA2 (0.47) | LMNAGAAALDH1A1MAPT | |
| SCHEMBL3577810 | 0.76 | CA2 (0.47) | LMNAGAAALDH1A1MAPT | |
| SCHEMBL7512761 | 0.75 | CA2 (0.52) | LMNA | |
| SCHEMBL9596744 | 0.75 | KMT2A (0.37) | L3MBTL1KMT2ALMNAGLAGAA | |
| SCHEMBL7515709 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL7509372 | 0.74 | CA2 (0.51) | LMNA | |
| SCHEMBL8950462 | 0.74 | CA2 (0.37) | L3MBTL1LMNAGAAALDH1A1CYP2C19 | |
| SCHEMBL7504951 | 0.72 | GBA1 (0.35) | KMT2AALDH1A1 | |
| SCHEMBL8950469 | 0.68 | KMT2A (0.39) | L3MBTL1KMT2ALMNAGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527801-B1 | THIOPHENE SULFONAMIDES USEFUL AS CARBONIC ANHYDRASE INHIBITORS | ALCON LAB INC (US) | 2002-07-31 | — | — | EP | disclosed |
| US-5240923-A | Treating glaucoma | ALCON LABORATORIES, INC. (US) | 1993-08-31 | — | — | US | disclosed |
| US-5153192-A | For controlling intraocular pressure | ALCON LABORATORIES, INC. (US) | 1992-10-06 | — | — | US | disclosed |