Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8950339 | 0.77 | CA2 (0.41) | KMT2ALMNACA2CA4NPSR1 | |
| SCHEMBL8950506 | 0.74 | GAA (0.31) | CA2CA4GAAALDH1A1MAPT | |
| SCHEMBL8950219 | 0.73 | SMN1; SMN2 (0.53) | KMT2ALMNACA2CA4MAPT | |
| SCHEMBL9057846 | 0.72 | KMT2A (0.38) | KMT2ALMNAGLAGAANPSR1 | |
| SCHEMBL8950133 | 0.71 | CA2 (0.36) | KMT2ACA2CA4NPSR1ALDH1A1 | |
| SCHEMBL8950135 | 0.69 | — | — | |
| SCHEMBL7508734 | 0.68 | L3MBTL1 (0.38) | KMT2ALMNAGLAGAANPSR1 | |
| SCHEMBL8950335 | 0.68 | — | — | |
| SCHEMBL9596744 | 0.65 | KMT2A (0.37) | KMT2ALMNAGLAGAANPSR1 | |
| SCHEMBL8950606 | 0.63 | CA2 (0.36) | KMT2ALMNACA2CA4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5538966-A | ENZYME INHIBITORS FOR TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1996-07-23 | — | — | US | disclosed |