Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Biphenyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B known ✓ | P49841 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMO | O15229 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL1839538 | 1.00 | ALDH1A1 (0.69) | ALDH1A1MAPTSMN1; SMN2MMP3BCL2L1 | |
| Biphenyl SCHEMBL190337 | 1.00 | ALDH1A1 (0.69) | ALDH1A1MAPTSMN1; SMN2MMP3BCL2L1 | |
| Biphenyl SCHEMBL377457 | 1.00 | ALDH1A1 (0.69) | ALDH1A1MAPTSMN1; SMN2MMP3BCL2L1 | |
| Biphenyl SCHEMBL1396421 | 1.00 | ALDH1A1 (0.69) | ALDH1A1MAPTSMN1; SMN2MMP3BCL2L1 | |
| Biphenyl SCHEMBL6843734 | 0.96 | ALDH1A1 (0.64) | ALDH1A1MAPTSMN1; SMN2MMP3BCL2L1 | |
| Biphenyl SCHEMBL9412797 | 0.96 | ALDH1A1 (0.64) | ALDH1A1MAPTSMN1; SMN2MMP3BCL2L1 | |
| Tannin Pyrogallol SCHEMBL10431034 | 0.96 | ALDH1A1 (0.64) | ALDH1A1MAPTSMN1; SMN2MMP3BCL2L1 | |
| Biphenyl SCHEMBL5573670 | 0.93 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2MMP3BCL2L1 | |
| Biphenyl SCHEMBL27463778 | 0.90 | SMN1; SMN2 (0.64) | ALDH1A1MAPTSMN1; SMN2MMP3BCL2L1 | |
| Biphenyl SCHEMBL10797777 | 0.89 | ALDH1A1 (0.64) | ALDH1A1MAPTSMN1; SMN2MMP3BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3406421-B1 | BIAXIALLY-STRETCHED POLYESTER FILM, LAMINATE AND PACKAGING BAG | TOYO BOSEKI (JP) | 2020-10-21 | — | — | EP | claimed |
| EP-3504277-B1 | COMPOSITE MATERIALS | BASF SE (DE) | 2020-10-07 | — | — | EP | claimed |
| EP-3529298-B1 | SEMI-CRYSTALLINE SEMI-AROMATIC POLYAMIDE AND COMPOSITIONS COMPRISING THE SAME | DSM IP ASSETS BV (NL) | 2020-09-16 | — | — | EP | claimed |
| EP-3287273-B1 | BIAXIALLY STRETCHED POLYESTER FILM | TOYO BOSEKI (JP) | 2020-05-06 | — | — | EP | claimed |
| EP-2716360-B9 | METHOD FOR PREPARING POROUS ORGANIC-INORGANIC HYBRID MATERIALS | KOREA RES INST CHEMICAL TECH (KR) | 2019-03-27 | — | — | EP | claimed |
| EP-2716360-B1 | METHOD FOR PREPARING POROUS ORGANIC-INORGANIC HYBRID MATERIALS | KOREA RES INST CHEMICAL TECH (KR) | 2018-10-31 | — | — | EP | claimed |
| EP-2789639-B1 | Process for the preparation of copolyesters based on 2,2,4,4-tetramethyl-1,3-cyclobutane diol and 1,4-cyclohexanedimethanol | EASTMAN CHEM CO (US) | 2017-01-25 | — | — | EP | claimed |
| EP-2152777-B1 | PROCESS FOR THE PREPARATION OF COPOLYESTERS BASED ON 2,2,4,4-TETRAMETHYL-1,3-CYCLOBUTANEDIOL AND 1,4-CYCLOHEXANDIMETHANOL | EASTMAN CHEM CO (US) | 2014-06-04 | — | — | EP | claimed |
| EP-1923428-B1 | POLYESTER RESIN AQUEOUS DISPERSION, COATING FILM OBTAINED FROM SAME, AND PACKAGING BAG USING SUCH COATING FILM | UNITIKA LTD (JP) | 2011-11-09 | — | — | EP | claimed |
| JP-2011524450-A | — | — | 2011-09-01 | — | — | JP | claimed |
| EP-0962459-B1 | DIACETAL COMPOSITION, PROCESS FOR THE PREPARATION OF THE SAME, NUCLEATING AGENT FOR POLYOLEFINS CONTAINING THE SAME, POLYOLEFIN RESIN COMPOSITIONS, AND MOLDINGS | NEW JAPAN CHEM CO LTD (JP) | 2003-10-01 | — | — | EP | claimed |
| EP-1055660-B1 | Process for producing highly pure aromatic polycarboxylic acid | MITSUBISHI GAS CHEMICAL CO (JP) | 2003-05-21 | — | — | EP | claimed |
| EP-0796296-B1 | POLYPHENYLENE ETHER BLENDS AND PROCESS FOR PRODUCING THEM | OPTATECH CORP (FI) | 2003-02-26 | — | — | EP | claimed |
| EP-0856025-B1 | CHOLESTERIC PHASE-FORMING POLYMERS AND THEIR USE | CELANESE VENTURES GMBH (DE) | 2003-01-15 | — | — | EP | claimed |
| EP-0759459-B1 | Thermoplastic resin composition superior in transparency and antistatic property | TEIJIN LTD (JP) | 2001-01-03 | — | — | EP | claimed |
| EP-0749451-B1 | FLAME RETARDANT POLYESTER COPOLYMERS | SOLUTIA INC (US) | 2000-08-02 | — | — | EP | claimed |
| EP-0653451-B1 | POLYESTER | KANEBO LTD (JP) | 1999-02-17 | — | — | EP | claimed |
| EP-0541702-B1 | BLENDS OF POLY(ETHYLENE TEREPHTHALATE) AND POLY(ETHYLENE NAPHTHALENEDICARBOXYLATE) CONTAINING A PHOSPHOROUS STABILIZER | EASTMAN CHEM CO (US) | 1996-09-11 | — | — | EP | claimed |
| EP-0401125-B1 | Biphenyl derivatives, process for preparing the same and intermediates therefor | TANABE SEIYAKU CO (JP) | 1994-08-24 | — | — | EP | claimed |
| EP-0378032-B1 | Blends of polycarbonates with polyesters from 4,4'-biphenyldicarboxylic acid and 1,6-hexanediol | EASTMAN KODAK CO (US) | 1994-03-23 | — | — | EP | claimed |