Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 6/20 | 0.70 |
| ▸ | CDK8 | P49336 | 6/20 | 0.70 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.52 |
| ▸ | CCR1 | P32246 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7500994 | 0.90 | CYP1A2 (0.63) | CCNCCDK8CYP1A2HTTKDM4E | |
| SCHEMBL7507392 | 0.88 | CCNC (0.69) | CCNCCDK8MAPKAPK2CYP1A2HTT | |
| SCHEMBL7507732 | 0.86 | HTR1A (0.70) | CCNCCDK8MAPKAPK2CYP1A2HTT | |
| SCHEMBL19160656 | 0.83 | CCNC (0.77) | CCNCCDK8MAPKAPK2CYP1A2HTT | |
| SCHEMBL21750458 | 0.83 | CCNC (1.00) | CCNCCDK8CYP1A2HTTKDM4E | |
| SCHEMBL7505625 | 0.83 | HTR1A (0.69) | CCNCCDK8CYP1A2HTTKDM4E | |
| SCHEMBL7505350 | 0.82 | CCNC (0.71) | CCNCCDK8CYP1A2HTTKDM4E | |
| SCHEMBL7500391 | 0.82 | CYP1A2 (0.78) | CCNCCDK8CYP1A2HTTKDM4E | |
| SCHEMBL7500265 | 0.78 | CCNC (0.64) | CCNCCDK8CYP1A2HTTKDM4E | |
| SCHEMBL7500219 | 0.77 | HTR1A (0.78) | CCNCCDK8MAPKAPK2HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326331-B1 | Substituted quinolines and cinnolines | DOW AGROSCIENCES LLC (US) | 2002-04-17 | — | — | EP | disclosed |