Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 12/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 12/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 12/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401199 | 0.78 | ADRA2A (0.45) | ADRA2AADRA2BADRA2CADRA1ACYP3A4 | |
| SCHEMBL9558819 | 0.75 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CADRA1ACYP3A4 | |
| SCHEMBL9558829 | 0.72 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CADRA1ACYP3A4 | |
| SCHEMBL11710024 | 0.71 | ADRA2A (0.73) | ADRA2AADRA2BADRA2CADRA1ACYP3A4 | |
| SCHEMBL11710014 | 0.71 | ADRA2A (0.73) | ADRA2AADRA2BADRA2CADRA1ACYP3A4 | |
| SCHEMBL11125378 | 0.71 | — | — | |
| SCHEMBL1726232 | 0.67 | SMN1; SMN2 (0.43) | ADRA2AADRA2BADRA2CADRA1ACYP3A4 | |
| SCHEMBL24533674 | 0.66 | — | — | |
| SCHEMBL10143149 | 0.66 | — | — | |
| SCHEMBL11356202 | 0.66 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CADRA1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1044194-A4 | RECEPTOR WITH AN AFFINITY FOR COMPOUNDS OF THE OXAZOLINE CLASS | UNIV MELBOURNE (AU) | 2002-01-09 | — | — | EP | disclosed |
| EP-1044194-A1 | RECEPTOR WITH AN AFFINITY FOR COMPOUNDS OF THE OXAZOLINE CLASS | THE UNIVERSITY OF MELBOURNE (AU) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999024411-A1 | RECEPTOR WITH AN AFFINITY FOR COMPOUNDS OF THE OXAZOLINE CLASS | THE UNIVERSITY OF MELBOURNE (AU) | 1999-05-20 | — | — | WO | disclosed |