Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6895329 | 0.92 | HAAO (0.35) | LMNACYP2C9SLC22A6SLC22A8POLB | |
| SCHEMBL7619023 | 0.77 | CYP1A2 (0.34) | ALDH1A1POLBMAPTRECQLTDP1 | |
| SCHEMBL8134119 | 0.75 | PTK2 (0.35) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL6723758 | 0.74 | LMNA (0.36) | LMNAALDH1A1HTTKDM4EHPGD | |
| SCHEMBL6419613 | 0.74 | RXRA (0.46) | SLC22A6SLC22A8RXRARXRBRXRG | |
| SCHEMBL6773319 | 0.74 | HPD (0.36) | — | |
| SCHEMBL6752193 | 0.73 | TSHR (0.39) | LMNAALDH1A1POLBKDM4ECYP1A2 | |
| SCHEMBL6773040 | 0.73 | MCL1 (0.33) | CYP1A2 | |
| SCHEMBL6772652 | 0.72 | VEGFA (0.41) | CYP1A2TSHR | |
| SCHEMBL8130863 | 0.72 | KDM4E (0.34) | LMNAALDH1A1POLBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188376-A1 | TRIKETONE DERIVATIVES AND HERBICIDES FOR LOWLAND FIELDS | Idemitsu Kosan Co., Ltd. (JP) | 2002-03-20 | — | — | EP | disclosed |
| US-6316390-B1 | THIOCHROMENE KETONE COMPOUNDS | IDEMITSU KOSAN CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |
| US-6159904-A | Pyrazole derivatives | IDEMITSU KOSAN CO., LTD. (JP) | 2000-12-12 | — | — | US | disclosed |
| EP-1043323-A1 | TRIKETONE DERIVATIVES | Idemitsu Kosan Co., Ltd. (JP) | 2000-10-11 | — | — | EP | disclosed |
| EP-0970956-A1 | PYRAZOLE DERIVATIVES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2000-01-12 | — | — | EP | disclosed |