Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 4/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511215 | 0.86 | LTA4H (0.43) | PDK2LTA4HPOLBBACE1DRD1 | |
| SCHEMBL7510883 | 0.86 | HRH3 (0.44) | PDK2LTA4HPOLBMEN1KMT2A | |
| SCHEMBL6605789 | 0.85 | F2 (0.47) | ESR1ESR2 | |
| SCHEMBL6967273 | 0.84 | PDK2 (0.45) | PDK2LTA4HPOLBMEN1KMT2A | |
| Oxalic Acid SCHEMBL6609694 | 0.83 | F2 (0.45) | ESR1ESR2 | |
| SCHEMBL6965066 | 0.82 | LTA4H (0.54) | PDK2LTA4HMEN1KMT2ADRD1 | |
| SCHEMBL6611377 | 0.74 | F2 (0.46) | PDK2ESR1ESR2 | |
| SCHEMBL6606510 | 0.74 | F2 (0.50) | ESR1ESR2 | |
| SCHEMBL6967241 | 0.73 | LTA4H (0.52) | LTA4HESR1 | |
| Lithium Ion SCHEMBL6611336 | 0.73 | LTA4H (0.39) | PDK2LTA4HPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244655-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001036414-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2001-05-25 | — | — | WO | disclosed |