Water

Water

SCHEMBL7511286

[Ca+2].[H+].[OH-].[OH-].[OH-]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL1252895 0.82
Water SCHEMBL6142606 0.82
SCHEMBL1662398 0.82
SCHEMBL219243 0.82
SCHEMBL3674149 0.82
Water SCHEMBL29152753 0.82
SCHEMBL9937825 0.82
Water SCHEMBL8143527 0.82
SCHEMBL516205 0.82
Water SCHEMBL27455594 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108083312-A A kind of carbonization reactor and preparation small particle, polymolecularity, the method for low oil factor nano-calcium carbonate 江西势通钙业有限公司 2018-05-29 CN claimed
EP-2620136-A1 Denture adhesive hydrogel with dry tack Combe Incorporated (US) 2013-07-31 EP claimed
CN-108083312-B A kind of carbonization reactor and preparation small particle, polymolecularity, low oil factor nanometer calcium carbonate method 江西势通钙业有限公司 2019-09-03 CN disclosed
CN-108148451-A A kind of compound base amount method agent and high intensity, the preparation method of low modulus silicone adhesive nano-calcium carbonate 江西势通钙业有限公司 2018-06-12 CN disclosed
CN-108083312-A A kind of carbonization reactor and preparation small particle, polymolecularity, the method for low oil factor nano-calcium carbonate 江西势通钙业有限公司 2018-05-29 CN disclosed
CN-107312269-A A kind of composite thermal stabilizer and preparation method thereof 郑州庆宏塑胶科技有限公司 2017-11-03 CN disclosed
US-6472079-B2 PRODUCT OF HYDROLYSIS AND CONDENSATION OF AN ORGANOSILICON COMPOUND; 1A OR 2A COMPOUND, ESPECIALLY CARBOXYLIC SALT; SOLVENT; EXCELLENT CRACKING RESISTANCE AFTER A PCT (PRESSURE COOKER TEST). JSR CORPORATION (JP) 2002-10-29 US disclosed
US-20020045693-A1 Composition for film formation, method of film formation and silica-based film JSR CORPORATION (JP) 2002-04-18 US disclosed
EP-1148105-A2 Composition for film formation, method of film formation, and silica-based film JSR Corporation (JP) 2001-10-24 EP disclosed