Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | PPARD | Q03181 | 5/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 1/20 | 0.34 |
| ▸ | ATP4B | P51164 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509113 | 0.91 | KCNH2 (0.34) | PTPN1PPARDKCNH2MAPTSMN1; SMN2 | |
| SCHEMBL7516627 | 0.90 | DRD2 (0.39) | PPARGPPARADRD2KCNH2MAPT | |
| SCHEMBL4442467 | 0.89 | MAPT (0.38) | PPARDKCNH2MAPTSMN1; SMN2 | |
| SCHEMBL7507160 | 0.88 | TDP1 (0.44) | DRD2KCNH2MAPTSMN1; SMN2 | |
| SCHEMBL7509782 | 0.86 | TDP1 (0.41) | PPARGPPARADRD2KCNH2 | |
| SCHEMBL7508005 | 0.85 | HTR1A (0.33) | PPARDPPARGPPARAKCNH2MAPT | |
| SCHEMBL7507094 | 0.84 | CETP (0.38) | PTPN1PPARDPPARGPPARACETP | |
| SCHEMBL7514067 | 0.84 | MAPT (0.36) | PPARGPPARAATP4AATP4BKCNH2 | |
| SCHEMBL7507843 | 0.83 | PTPN1 (0.38) | PTPN1PPARDPPARGPPARAKCNH2 | |
| SCHEMBL7508031 | 0.83 | HSD17B10 (0.39) | PPARGPPARACETPKCNH2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206472-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AS NEUROTROPHIN PRODUCTION/SECRETION PROMOTING AGENT | Takeda Chemical Industries, Ltd. (JP) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001014372-A2 | OXAZOLE AND THIAZOLE DERIVATIVES AS NEUROTROPHIN PRODUCTION/SECRETION PROMOTING AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-01 | — | — | WO | disclosed |