Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AGER | Q15109 | 3/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442467 | 0.93 | MAPT (0.38) | KCNH2TDP1L3MBTL1SMN1; SMN2MEN1 | |
| SCHEMBL7507160 | 0.92 | TDP1 (0.44) | DRD2DRD4DRD3KCNH2RXFP1 | |
| SCHEMBL7509782 | 0.91 | TDP1 (0.41) | DRD2DRD4DRD3KCNH2PPARG | |
| SCHEMBL7511397 | 0.90 | PTPN1 (0.41) | DRD2KCNH2PPARGPPARASMN1; SMN2 | |
| SCHEMBL7509113 | 0.90 | KCNH2 (0.34) | KCNH2TDP1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL7508031 | 0.89 | HSD17B10 (0.39) | KCNH2PPARGPPARATDP1L3MBTL1 | |
| SCHEMBL7514067 | 0.88 | MAPT (0.36) | KCNH2PPARGPPARATDP1L3MBTL1 | |
| SCHEMBL7508005 | 0.87 | HTR1A (0.33) | KCNH2PPARGPPARATDP1L3MBTL1 | |
| SCHEMBL7512113 | 0.86 | CETP (0.32) | TDP1 | |
| SCHEMBL4440984 | 0.86 | POLB (0.40) | KCNH2RXFP1TDP1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1206472-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AS NEUROTROPHIN PRODUCTION/SECRETION PROMOTING AGENT | Takeda Chemical Industries, Ltd. (JP) | 2002-05-22 | — | — | EP | disclosed |
| WO-2001014372-A2 | OXAZOLE AND THIAZOLE DERIVATIVES AS NEUROTROPHIN PRODUCTION/SECRETION PROMOTING AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-01 | — | — | WO | disclosed |