SCHEMBL7511680

SCHEMBL7511680

CC(C)(C)c1cc(C(=O)OC2CC(C)(C)N(O)C(C)(C)C2)cc(C(C)(C)C)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.48
HTT P42858 2/20 0.48
TSHR P16473 2/20 0.43
SERPINE1 P05121 2/20 0.41
LMNA P02545 1/20 0.38
RECQL P46063 1/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.37
ALOX5 P09917 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
ALDH1A1 P00352 2/20 0.36
ESR1 P03372 1/20 0.36
HSD17B10 Q99714 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
GALR3 O60755 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9765824 0.93 GAA (0.43) GAAHTTTSHRSERPINE1LMNA
SCHEMBL9400310 0.87 KMT2A (0.53) GAAHTTTSHRSERPINE1LMNA
SCHEMBL9588684 0.87 TSHR (0.47) GAAHTTTSHRSERPINE1LMNA
SCHEMBL18072216 0.85 GAA (0.57) GAAHTTTSHRSERPINE1KMT2A
SCHEMBL1264011 0.85 TSHR (0.64) GAAHTTTSHRSERPINE1LMNA
SCHEMBL10817965 0.84 GAA (0.58) GAAHTTTSHRSERPINE1LMNA
SCHEMBL9382414 0.84 SERPINE1 (0.41) GAAHTTTSHRSERPINE1LMNA
SCHEMBL11271389 0.84 TSHR (0.39) GAAHTTTSHRSERPINE1LMNA
SCHEMBL21236208 0.82 GAA (0.43) GAAHTTTSHRLMNAKMT2A
SCHEMBL9588919 0.82 TSHR (0.43) GAAHTTTSHRSERPINE1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0467848-B1 Stabilized monomer compositions CIBA GEIGY AG (CH) 1996-01-31 EP claimed
EP-0467848-A1 Stabilized monomer compositions CIBA-GEIGY AG (CH) 1992-01-22 EP claimed
US-5006577-A Durable, weatherproof CIBA-GEIGY CORPORATION (US) 1991-04-09 US claimed
EP-0309401-B2 Stabilization of coatings with N-hydroxy hindered amines CIBA SC HOLDING AG (CH) 2002-06-05 EP disclosed
EP-0467848-B1 Stabilized monomer compositions CIBA GEIGY AG (CH) 1996-01-31 EP disclosed
EP-0309401-B1 Stabilization of coatings with N-hydroxy hindered amines CIBA GEIGY AG (CH) 1994-10-26 EP disclosed
US-5290888-A N-hydroxy substituted piperidines CIBA-GEIGY CORPORATION (US) 1994-03-01 US disclosed
EP-0467848-A1 Stabilized monomer compositions CIBA-GEIGY AG (CH) 1992-01-22 EP disclosed
US-5064883-A Stabilization of acid catalyzed thermoset resins with n-hydroxy hindered amines CIBA-GEIGY CORPORATION (US) 1991-11-12 US disclosed
US-5006577-A Durable, weatherproof CIBA-GEIGY CORPORATION (US) 1991-04-09 US disclosed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US disclosed