Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | VCAM1 | P19320 | 10/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511680 | 0.93 | GAA (0.48) | GAAHTTTSHRSERPINE1LMNA | |
| SCHEMBL9400310 | 0.81 | KMT2A (0.53) | GAAHTTTSHRSERPINE1LMNA | |
| SCHEMBL9588684 | 0.81 | TSHR (0.47) | GAAHTTTSHRSERPINE1LMNA | |
| SCHEMBL11271389 | 0.80 | TSHR (0.39) | GAAHTTTSHRSERPINE1LMNA | |
| SCHEMBL18072216 | 0.79 | GAA (0.57) | GAAHTTTSHRSERPINE1KMT2A | |
| SCHEMBL1264011 | 0.79 | TSHR (0.64) | GAAHTTTSHRSERPINE1LMNA | |
| SCHEMBL9382414 | 0.78 | SERPINE1 (0.41) | GAAHTTTSHRSERPINE1LMNA | |
| SCHEMBL10817965 | 0.78 | GAA (0.58) | GAAHTTTSHRSERPINE1LMNA | |
| SCHEMBL21236208 | 0.76 | GAA (0.43) | GAAHTTTSHRLMNAKMT2A | |
| SCHEMBL9588919 | 0.76 | TSHR (0.43) | GAAHTTTSHRSERPINE1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5064883-A | Stabilization of acid catalyzed thermoset resins with n-hydroxy hindered amines | CIBA-GEIGY CORPORATION (US) | 1991-11-12 | — | — | US | disclosed |
| US-5004770-A | Light, heat, and oxygen resistant | CIBA-GEIGY CORPORATION (US) | 1991-04-02 | — | — | US | disclosed |
| US-4831134-A | N-hydroxy hindered amine stabilizers | CIBA-GEIGY CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |