Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9400310 | 0.90 | KMT2A (0.53) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL1264011 | 0.88 | TSHR (0.64) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL7511680 | 0.87 | GAA (0.48) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL9588919 | 0.84 | TSHR (0.43) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL9382414 | 0.82 | SERPINE1 (0.41) | TSHRKMT2AALDH1A1SERPINE1GAA | |
| SCHEMBL10817965 | 0.82 | GAA (0.58) | TSHRKMT2ASERPINE1GAALMNA | |
| SCHEMBL11271389 | 0.81 | TSHR (0.39) | TSHRKMT2ASERPINE1GAALMNA | |
| SCHEMBL9765824 | 0.81 | GAA (0.43) | TSHRKMT2ASERPINE1GAALMNA | |
| SCHEMBL9591172 | 0.81 | TSHR (0.63) | TSHRKMT2AALDH1A1ESR1HSD17B10 | |
| SCHEMBL13474857 | 0.81 | TSHR (0.54) | TSHRKMT2AALDH1A1ESR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5204473-A | O-substituted N-hydroxy hindered amine stabilizers | CIBA-GEIGY CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |