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SCHEMBL9400310

SCHEMBL9400310

CC(C)(C)c1cc(C(=O)OC2CC(C)(C)N(OC(=O)c3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)C(C)(C)C2)cc(C(C)(C)C)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.53
▸ TSHR P16473 2/20 0.53
▸ ALDH1A1 P00352 1/20 0.51
▸ ESR1 P03372 1/20 0.51
▸ HSD17B10 Q99714 1/20 0.51
▸ SERPINE1 P05121 2/20 0.39
▸ GAA P10253 4/20 0.37
▸ LMNA P02545 1/20 0.37
▸ RECQL P46063 1/20 0.37
▸ MEN1 O00255 3/20 0.36
▸ HTT P42858 2/20 0.36
▸ ALOX5 P09917 1/20 0.35
▸ PTGS1 P23219 1/20 0.35
▸ PTGS2 P35354 1/20 0.35
▸ SMN1; SMN2 Q16637 3/20 0.34
▸ GALR3 O60755 1/20 0.34
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1264011 0.93 TSHR (0.64) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL9588684 0.90 TSHR (0.47) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL7511680 0.87 GAA (0.48) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL9588919 0.84 TSHR (0.43) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL10817965 0.82 GAA (0.58) KMT2ATSHRSERPINE1GAALMNA
SCHEMBL9382414 0.82 SERPINE1 (0.41) KMT2ATSHRALDH1A1SERPINE1GAA
SCHEMBL11271389 0.81 TSHR (0.39) KMT2ATSHRSERPINE1GAALMNA
SCHEMBL9765824 0.81 GAA (0.43) KMT2ATSHRSERPINE1GAALMNA
SCHEMBL9413674 0.80 GAA (0.39) KMT2ATSHRALDH1A1ESR1HSD17B10
SCHEMBL11270401 0.80 TSHR (0.40) KMT2ATSHRALDH1A1ESR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300647-A Light stabilizers for polyolefins, other polymers CIBA-GEIGY CORPORATION (US) 1994-04-05 — — US claimed
EP-0309400-B1 N-acyloxy hindered amine stabilizers CIBA GEIGY AG (CH) 1994-03-02 — — EP claimed
US-5124378-A Resin containign N-Hydroxyl hindered amine oxidative and light stabilizers CIBA-GEIGY CORPORATION (US) 1992-06-23 — — US claimed
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 — — US claimed
EP-0365481-A1 Polymeric substrates stabilized with N-substituted hindered amines CIBA-GEIGY AG (CH) 1990-04-25 — — EP claimed
EP-0309400-A2 N-acyloxy hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 — — EP claimed
US-5300647-A Light stabilizers for polyolefins, other polymers CIBA-GEIGY CORPORATION (US) 1994-04-05 — — US disclosed
EP-0309400-B1 N-acyloxy hindered amine stabilizers CIBA GEIGY AG (CH) 1994-03-02 — — EP disclosed
US-5124378-A Resin containign N-Hydroxyl hindered amine oxidative and light stabilizers CIBA-GEIGY CORPORATION (US) 1992-06-23 — — US disclosed
US-5112890-A Piperidine compound with oxygen bonded to ring nitrogen CIBA-GEIGY CORPORATION (US) 1992-05-12 — — US disclosed
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 — — US disclosed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 — — US disclosed
EP-0365481-A1 Polymeric substrates stabilized with N-substituted hindered amines CIBA-GEIGY AG (CH) 1990-04-25 — — EP disclosed
EP-0309400-A2 N-acyloxy hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 — — EP disclosed