SCHEMBL7511779

SCHEMBL7511779

CC1(C)CC(C(C2CC(C)(C)N(O)C(C)(C)C2)C(C(=O)O)C(=O)O)CC(C)(C)N1O

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
CYP2C19 P33261 1/20 0.32
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
APLNR P35414 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8162902 0.78 GAA (0.38) GAAL3MBTL1KDM4EALDH1A1ALOX15
SCHEMBL10575972 0.74 POLB (0.37) GAAKDM4EALOX15TSHRHTT
SCHEMBL7506204 0.74 GAA (0.34) GAAL3MBTL1KDM4EALDH1A1ALOX15
SCHEMBL7187151 0.73 GAA (0.33) GAAL3MBTL1KDM4EALDH1A1ALOX15
SCHEMBL26977202 0.72 CHRM1 (0.35) GAAL3MBTL1KDM4EALDH1A1ALOX15
SCHEMBL11960960 0.70 GAA (0.44) GAAL3MBTL1KDM4EALDH1A1ALOX15
SCHEMBL7879384 0.69 CA2 (0.37) GAAL3MBTL1ALDH1A1ALOX15
SCHEMBL416167 0.69 APLNR (0.58) GAAL3MBTL1KDM4EALDH1A1ALOX15
SCHEMBL26977293 0.68 GPR84 (0.39)
SCHEMBL7191030 0.68 CYP1A2 (0.34) GAAL3MBTL1ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0309401-B2 Stabilization of coatings with N-hydroxy hindered amines CIBA SC HOLDING AG (CH) 2002-06-05 EP claimed
EP-0309401-B1 Stabilization of coatings with N-hydroxy hindered amines CIBA GEIGY AG (CH) 1994-10-26 EP claimed
US-4831134-A N-hydroxy hindered amine stabilizers CIBA-GEIGY CORPORATION (US) 1989-05-16 US claimed
US-4831134-A N-hydroxy hindered amine stabilizers CIBA-GEIGY CORPORATION (US) 1989-05-16 US disclosed