Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11560765 | 0.75 | MAPT (0.46) | KDM4ELMNAKMT2AMAPTTSHR | |
| SCHEMBL5444623 | 0.72 | TDP1 (0.50) | KDM4ELMNAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL999403 | 0.71 | LMNA (0.55) | KDM4ELMNAALOX12KMT2AMAPT | |
| SCHEMBL2007845 | 0.70 | CA12 (0.46) | LMNAKMT2ATP53ALDH1A1GAA | |
| SCHEMBL27733088 | 0.70 | KDM4E (0.49) | KDM4ELMNAALOX12KMT2AMAPT | |
| SCHEMBL19705421 | 0.68 | MAPT (0.51) | KDM4EMAPTTSHRALOX15ALDH1A1 | |
| SCHEMBL26092394 | 0.68 | KDM4E (0.49) | KDM4ELMNAALOX12KMT2APARP2 | |
| SCHEMBL30361205 | 0.68 | KDM4E (0.49) | KDM4ELMNAALOX12KMT2APARP2 | |
| SCHEMBL8473544 | 0.68 | LMNA (0.41) | KDM4ELMNAALOX12KMT2AMAPT | |
| SCHEMBL1031322 | 0.67 | LTB4R (0.53) | KDM4ELMNAALOX12KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0731091-B1 | 2-OXOINDOLINE DERIVATIVES AS CHOLECYSTOKININ RECEPTOR ANTAGONISTS | TANABE SEIYAKU CO (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-5807883-A | GASTROINTESTINAL DISORDERS; PANCREATITIS | TANABE SEIYAKU CO., LTD. (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0731091-A1 | 2-OXOINDOLINE DERIVATIVE | TANABE SEIYAKU CO., LTD. (JP) | 1996-09-11 | — | — | EP | disclosed |