Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5444623 | 0.87 | TDP1 (0.50) | MAPTTDP1ALDH1A1KDM4EPDE4D | |
| SCHEMBL13607855 | 0.87 | MAPT (0.57) | MAPTTDP1ALDH1A1KDM4EPDE4D | |
| SCHEMBL2007845 | 0.82 | CA12 (0.46) | ALDH1A1SMN1; SMN2LMNAGAAHTT | |
| SCHEMBL9053891 | 0.82 | TDP1 (0.42) | MAPTTDP1ALDH1A1KDM4EPDE4D | |
| SCHEMBL7469868 | 0.81 | MAPT (0.58) | MAPTTDP1ALDH1A1KDM4EPDE4D | |
| SCHEMBL3782773 | 0.77 | MAPT (0.62) | MAPTTDP1ALDH1A1KDM4EPDE4D | |
| SCHEMBL19705421 | 0.76 | MAPT (0.51) | MAPTTDP1ALDH1A1KDM4EMAPK1 | |
| SCHEMBL344646 | 0.76 | NPC1 (0.52) | MAPTTDP1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL7511904 | 0.75 | KDM4E (0.38) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL18475471 | 0.74 | PTGS2 (0.46) | MAPTTDP1ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4151179-A | ANTIINFLAMMATORY AGENTS | FISONS LIMITED (GB) | 1979-04-24 | — | — | US | disclosed |