Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 5/20 | 0.47 |
| ▸ | TACR1 | P25103 | 6/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6543335 | 0.98 | OPRM1 (0.46) | OPRM1TACR1HTR2AOPRD1OPRK1 | |
| SCHEMBL3018551 | 0.83 | OPRM1 (0.57) | OPRM1TACR1HTR2AOPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL8367126 | 0.81 | DRD3 (0.45) | OPRM1TACR1HTR2AOPRD1OPRK1 | |
| SCHEMBL28865491 | 0.81 | OPRM1 (0.48) | OPRM1TACR1HTR2AOPRD1OPRK1 | |
| SCHEMBL8329089 | 0.79 | OPRM1 (0.55) | OPRM1TACR1HTR2AOPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL18424795 | 0.78 | OPRM1 (0.54) | OPRM1TACR1HTR2AOPRD1OPRK1 | |
| SCHEMBL11536155 | 0.75 | OPRM1 (0.46) | OPRM1TACR1HTR2AOPRD1OPRK1 | |
| SCHEMBL11535461 | 0.75 | OPRM1 (0.46) | OPRM1TACR1HTR2AOPRD1OPRK1 | |
| SCHEMBL24944034 | 0.74 | OPRM1 (0.48) | OPRM1TACR1HTR2AOPRD1OPRK1 | |
| SCHEMBL8827332 | 0.74 | DRD3 (0.62) | OPRM1OPRD1OPRK1OPRL1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1241168-A1 | Human NK3 receptor-selective antagonist compounds, process for their obtention and pharmaceutical compositons containing them | SANOFI-SYNTHELABO (FR) | 2002-09-18 | — | — | EP | disclosed |
| EP-1019373-A1 | NOVEL HUMAN NK 3? RECEPTOR-SELECTIVE ANTAGONIST COMPOUNDS, METHOD FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI-SYNTHELABO (FR) | 2000-07-19 | — | — | EP | disclosed |
| WO-1997010211-A1 | NOVEL HUMAN NK3 RECEPTOR-SELECTIVE ANTAGONIST COMPOUNDS, METHOD FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI (FR) | 1997-03-20 | — | — | WO | disclosed |