Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.55 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.55 |
| ▸ | TACR1 | P25103 | 6/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL18424795 | 0.98 | OPRM1 (0.54) | OPRM1OPRD1OPRK1OPRL1TACR1 | |
| SCHEMBL3018551 | 0.86 | OPRM1 (0.57) | OPRM1OPRD1OPRK1OPRL1TACR1 | |
| SCHEMBL28865491 | 0.83 | OPRM1 (0.48) | OPRM1OPRD1OPRK1OPRL1TACR1 | |
| SCHEMBL10603880 | 0.83 | OPRM1 (0.59) | OPRM1OPRD1OPRK1OPRL1DRD3 | |
| SCHEMBL28818442 | 0.83 | OPRM1 (0.39) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL18895934 | 0.83 | DRD2 (0.50) | OPRM1OPRD1OPRK1OPRL1AKT2 | |
| SCHEMBL6928751 | 0.82 | OPRM1 (0.40) | OPRM1OPRD1OPRK1OPRL1TACR1 | |
| SCHEMBL15043695 | 0.81 | OPRM1 (0.58) | OPRM1OPRD1OPRK1OPRL1DRD3 | |
| Hydrochloric Acid SCHEMBL29041993 | 0.81 | OPRM1 (0.38) | OPRM1OPRD1OPRK1OPRL1TACR1 | |
| Hydrochloric Acid SCHEMBL8367126 | 0.80 | DRD3 (0.45) | OPRM1OPRD1OPRK1OPRL1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4022791-A | ANALGESICS, TRANQUILIZERS | PFIZER INC. (US) | 1977-05-10 | — | — | US | claimed |
| US-5925642-A | ANTITUMOR, ANTIMETASTASIS AGENTS; DRUG RESISTANCE MODULATORS; SYNERGISTIC MIXTURES WITH ANTIBIOTICS AND CYTOSTATIC AGENTS; SIDE EFFECT REDUCTION | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-07-20 | — | — | US | disclosed |
| US-5668131-A | CONTROLLING HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1997-09-16 | — | — | US | disclosed |
| US-4140781-A | Analgesic and neuraleptic 2-piperidinoalkyl-1,4-benzodioxans | CIBA-GEIGY CORPORATION (US) | 1979-02-20 | — | — | US | disclosed |
| US-4129655-A | Neuroleptic 2-piperidinoalkyl-1,4-benzodioxans | CIBA-GEIGY CORPORATION (US) | 1978-12-12 | — | — | US | disclosed |
| US-4104396-A | NEUROLEPTIC, ANALGESIC | CIBA-GEIGY CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |