Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.62 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.62 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.62 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL28172259 | 0.88 | LMNA (0.48) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Hydrazine SCHEMBL27696750 | 0.87 | LMNA (0.44) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| SCHEMBL4816014 | 0.87 | LMNA (0.50) | GLRA1SLC6A9OR51E2LMNAHDAC3 | |
| SCHEMBL27023 | 0.87 | — | — | |
| SCHEMBL1741233 | 0.86 | GABRR1 (0.52) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Hydrochloric Acid SCHEMBL4161362 | 0.84 | GABRR1 (0.50) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL6135588 | 0.84 | GLRA1 (0.50) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Water SCHEMBL11785760 | 0.83 | LMNA (0.47) | GLRA1SLC6A9OR51E2LMNAHDAC3 | |
| SCHEMBL3464176 | 0.83 | LMNA (0.47) | LMNAHDAC3TSHRHDAC1HDAC2 | |
| SCHEMBL10627876 | 0.83 | LMNA (0.47) | GLRA1SLC6A9OR51E2LMNAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563215-B | Glycine production process | 上海蓝科石化环保科技股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-106748839-A | A kind of glycine and the clean preparation method of iminodiacetic acid coproduction | 重庆紫光化工股份有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-104003830-B | Amino acid separation and the method for iminodicarboxylic acid from the aqueous solution of amino acid whose alkali metal salt | 重庆紫光化工股份有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-204724028-U | The apparatus system of a kind of coproduction amino acid and analog thereof | CHONGQING UNISPLENDOUR CHEM CO | 2015-10-28 | — | — | CN | disclosed |
| CN-104710319-A | Green environmentally-friendly method for combined production of amino acid and analog thereof by using membrane integration technology | CHONGQING UNISPLENDOUR CHEM CO | 2015-06-17 | — | — | CN | disclosed |
| CN-100543008-C | Method for purifying amino acid | ASAHI CHEMICAL CORP (JP) | 2009-09-23 | — | — | CN | disclosed |
| CN-1950327-A | Method of purifying amino acid | ASAHI CHEMICAL CORP (JP) | 2007-04-18 | — | — | CN | disclosed |
| EP-0877080-B1 | HIGH-DENSITY GRANULATED DETERGENT COMPOSITION | KAO CORP (JP) | 2002-01-02 | — | — | EP | disclosed |