Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18098648 | 0.88 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL27513818 | 0.86 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL3393465 | 0.84 | MGAM (0.44) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL3393466 | 0.84 | MGAM (0.44) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL2460611 | 0.83 | ALDH1A1 (0.56) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL7509155 | 0.83 | CA2 (0.46) | ALDH1A1LMNAHSD17B10KMT2AMAPT | |
| SCHEMBL3394079 | 0.81 | MGAM (0.41) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL6829979 | 0.81 | ZDHHC7 (0.42) | KMT2AMAPTMEN1L3MBTL1CPB2 | |
| SCHEMBL3394073 | 0.81 | MGAM (0.41) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL7512070 | 0.80 | ZDHHC7 (0.44) | KMT2AMAPTMEN1L3MBTL1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4015511-A1 | OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS | CARNEGIE MELLON UNIVERSITY (US) | 2022-06-22 | — | — | EP | disclosed |
| EP-3353157-B1 | OXIDATION CATALYSTS BASED ON MACROCYCLIC COMPOUNDS | UNIV CARNEGIE MELLON (US) | 2021-11-24 | — | — | EP | disclosed |
| EP-0914206-B1 | LONG-LIVED HOMOGENOUS OXIDATION CATALYSTS | UNIV CARNEGIE MELLON (US) | 2002-12-11 | — | — | EP | disclosed |
| EP-0159599-B1 | PROCESS FOR THE PREPARATION OF ALCOXYMETHYLENE COMPOUNDS OF ESTERS OF ACETIC ACID AND SUBSTITUTED ACETIC ACID | HÜLS AKTIENGESELLSCHAFT (DE) | 1989-08-02 | — | — | EP | disclosed |
| US-4665218-A | Method for the preparation of alkoxymethylene compounds of acetic esters and substituted acetic esters | DYNAMIT NOBEL AG (DE) | 1987-05-12 | — | — | US | disclosed |