Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 9/20 | 0.52 |
| ▸ | CAPNS1 | P04632 | 4/20 | 0.51 |
| ▸ | CTSK | P43235 | 7/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 4/20 | 0.41 |
| ▸ | CASP3 | P42574 | 4/20 | 0.41 |
| ▸ | CASP7 | P55210 | 4/20 | 0.41 |
| ▸ | CASP6 | P55212 | 3/20 | 0.41 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517808 | 0.92 | CAPN1 (0.43) | CAPN1CAPNS1CTSKCTSLCTSS | |
| SCHEMBL7515359 | 0.89 | CAPN1 (0.56) | CAPN1CAPNS1CASP1CASP3CASP7 | |
| SCHEMBL7512998 | 0.82 | CAPN1 (0.53) | CAPN1CAPNS1CTSKCTSLCTSS | |
| SCHEMBL7514161 | 0.81 | CAPN1 (0.57) | CAPN1CAPNS1CTSKCTSLCTSS | |
| SCHEMBL7511787 | 0.80 | CAPN1 (0.44) | CAPN1CAPNS1CTSKCTSLCTSS | |
| SCHEMBL3577128 | 0.80 | CTSK (0.62) | CAPN1CAPNS1CTSKCTSLCTSS | |
| SCHEMBL8406499 | 0.80 | CTSK (0.62) | CAPN1CAPNS1CTSKCTSLCTSS | |
| SCHEMBL7514109 | 0.80 | CTSK (0.62) | CAPN1CAPNS1CTSKCTSLCTSS | |
| SCHEMBL7525753 | 0.78 | CTSK (0.61) | CAPN1CAPNS1CTSKCTSLCTSS | |
| SCHEMBL8408050 | 0.76 | CAPN1 (0.51) | CAPN1CAPNS1CASP1CASP3CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641800-B1 | Lactol derivatives as inhibitors of cathepsin L | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-01-16 | — | — | EP | claimed |
| EP-0641800-B1 | Lactol derivatives as inhibitors of cathepsin L | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-01-16 | — | — | EP | disclosed |