⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7521661 | 0.84 | KDM4E (0.31) | — | |
| SCHEMBL7529819 | 0.76 | — | — | |
| SCHEMBL7527848 | 0.75 | ALOX5 (0.37) | — | |
| SCHEMBL7523796 | 0.72 | ALOX15 (0.38) | — | |
| SCHEMBL7527960 | 0.71 | HPN (0.41) | — | |
| SCHEMBL7517269 | 0.69 | ESR1 (0.32) | — | |
| SCHEMBL7522333 | 0.69 | MEN1 (0.38) | — | |
| SCHEMBL7517845 | 0.68 | — | — | |
| SCHEMBL7526589 | 0.68 | ESR1 (0.32) | — | |
| SCHEMBL7522227 | 0.67 | ESR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900225-B1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | AVENTIS PHARMA INC (US) | 2002-01-30 | — | — | EP | disclosed |
| US-5608095-A | Alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-04 | — | — | US | disclosed |