Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | S100B | P04271 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | LGMN | Q99538 | 3/20 | 0.52 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28147210 | 0.89 | GAA (0.69) | MAPTGAAHTTMAPK1KDM4E | |
| Sulfuric Acid SCHEMBL7510988 | 0.88 | ALDH1A1 (0.52) | MAPTGAAHTTMAPK1KDM4E | |
| SCHEMBL7805793 | 0.86 | GAA (0.46) | MAPTGAAHTTMAPK1KDM4E | |
| SCHEMBL14280213 | 0.86 | LGMN (0.71) | MAPTGAAHTTMAPK1KDM4E | |
| SCHEMBL15041150 | 0.82 | MAPT (0.45) | MAPTGAAHTTMAPK1KDM4E | |
| Sulfuric Acid SCHEMBL7807267 | 0.81 | ALDH1A1 (0.54) | MAPTGAAHTTMAPK1KDM4E | |
| SCHEMBL7514624 | 0.81 | ALDH1A1 (0.53) | MAPTGAAHTTMAPK1KDM4E | |
| Sulfuric Acid SCHEMBL7808232 | 0.80 | ALDH1A1 (0.57) | MAPTGAAHTTMAPK1KDM4E | |
| Sulfuric Acid SCHEMBL7809582 | 0.80 | ALDH1A1 (0.57) | MAPTGAAHTTMAPK1KDM4E | |
| Hydrochloric Acid SCHEMBL16755395 | 0.80 | MAPT (0.44) | MAPTGAAHTTMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0917531-B1 | PIPERAZINE DERIVATIVES AND OXYDATION DYES | SCHWARZKOPF GMBH HANS (DE) | 2002-01-09 | — | — | EP | disclosed |
| EP-0917531-A1 | PIPERAZINE DERIVATIVES AND OXYDATION DYES | Hans Schwarzkopf GmbH & Co. KG (DE) | 1999-05-26 | — | — | EP | disclosed |
| WO-1998001434-A1 | NEW PIPERAZINE DERIVATIVES AND OXYDATION DYES | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 1998-01-15 | — | — | WO | disclosed |