Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4512580 | 0.75 | DGAT1 (0.38) | — | |
| SCHEMBL4506073 | 0.70 | KEAP1 (0.39) | — | |
| SCHEMBL27856987 | 0.70 | DGAT1 (0.39) | — | |
| SCHEMBL13341770 | 0.65 | TSHR (0.46) | MEN1KMT2ATDP1 | |
| SCHEMBL1548068 | 0.63 | CA1 (0.33) | — | |
| SCHEMBL29175217 | 0.62 | DGAT1 (0.38) | — | |
| SCHEMBL21374051 | 0.62 | PIK3CA (0.35) | TRPM8 | |
| SCHEMBL28388849 | 0.59 | DGAT1 (0.42) | — | |
| SCHEMBL6129758 | 0.59 | USP2 (0.49) | MEN1KMT2ATDP1 | |
| SCHEMBL23492884 | 0.59 | ESR1 (0.33) | MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | disclosed |