Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | GAA | P10253 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | TPMT | P51580 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2810884 | 0.85 | HCAR1 (0.46) | HCAR1KDM4EGAAHSD17B10GFER | |
| SCHEMBL10315998 | 0.78 | KDM4E (0.52) | HCAR1KDM4EGAAHSD17B10GFER | |
| SCHEMBL2892410 | 0.78 | KEAP1 (0.47) | HCAR1KDM4EGAAHSD17B10GFER | |
| SCHEMBL13284093 | 0.76 | HCAR1 (0.39) | HCAR1KDM4EGAAHSD17B10GFER | |
| SCHEMBL6086090 | 0.76 | KDM4E (0.46) | HCAR1KDM4EGAAHSD17B10GFER | |
| SCHEMBL23526674 | 0.73 | KDM4E (0.40) | HCAR1KDM4EGAAHSD17B10GFER | |
| SCHEMBL29945788 | 0.73 | KDM4E (0.40) | HCAR1KDM4EGAAHSD17B10GFER | |
| SCHEMBL2218644 | 0.72 | CA12 (0.56) | KMT2ACA12CA1CA2CA7 | |
| SCHEMBL10281394 | 0.72 | CDC25B (0.47) | HCAR1KDM4EGAAHSD17B10GFER | |
| SCHEMBL1000015 | 0.71 | CA12 (0.48) | KDM4EGAAHSD17B10GFERMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087842-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRIDONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |