SCHEMBL1000015

SCHEMBL1000015

Nc1cc(C(=O)O)cc(N)c1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA7 P43166 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
KDM4E B2RXH2 6/20 0.47
ALDH1A1 P00352 4/20 0.47
GAA P10253 4/20 0.47
MAPT P10636 3/20 0.47
HPGD P15428 3/20 0.47
THRB P10828 2/20 0.47
HTT P42858 1/20 0.47
GFER P55789 1/20 0.47
PLEC Q15149 1/20 0.47
TPMT P51580 3/20 0.46
HSD17B10 Q99714 3/20 0.46
LMNA P02545 3/20 0.46
TP53 P04637 2/20 0.46
TDP1 Q9NUW8 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3684356 0.85 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL3940128 0.85 KDM4E (0.45) CA12CA1CA2CA7CA9
SCHEMBL1759318 0.84 TTR (0.56) CA12CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL4299803 0.84 MAPT (0.45) CA12CA1CA2CA7CA9
SCHEMBL1759305 0.84 TTR (0.56) CA12CA1CA2CA7CA9
SCHEMBL1509519 0.84 KDM4E (0.48) CA12CA1CA2CA7CA9
SCHEMBL6051288 0.81 CA12 (0.46) CA12CA1CA2CA7CA9
SCHEMBL2191755 0.81 ALDH1A1 (0.56) CA12CA1CA2CA7CA9
SCHEMBL15016383 0.80 CA12 (0.37) CA12CA1CA2CA7CA9
SCHEMBL15016382 0.80 CDC25B (0.61) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1576093-A4 3-DEOXYGLUCOSONE AND SKIN DYNAMIS THERAPEUTICS INC (US) 2009-07-08 EP claimed
US-20070065443-A1 Fructoseamine 3 kinase and the formation of collagen and elastin DYNAMIS THERAPEUTICS, INC. 2007-03-22 US claimed
EP-1753861-A2 FRUCTOSEAMINE 3 KINASE AND THE FORMATION OF COLLAGEN AND ELASTIN Dynamis Therapeutics, Inc. (US) 2007-02-21 EP claimed
EP-1576093-A2 3-DEOXYGLUCOSONE AND SKIN Dynamis Therapeutics, Inc. (US) 2005-09-21 EP claimed
WO-2005079463-A2 FRUCTOSEAMINE 3 KINASE AND THE FORMATION OF COLLAGEN AND ELASTIN DYNAMIS THERAPEUTICS, INC. (US) 2005-09-01 WO claimed
US-20050159383-A1 Administering enzyme inhibitors; wrinkling and aging resistance; prevents formation Advanced Glycation End Products (AGEs) DYNAMIS THERAPEUTICS, INC. 2005-07-21 US claimed
US-20030219440-A1 3-deoxyglucosone and skin DYNAMIS THERAPEUTICS, INC. 2003-11-27 US claimed
WO-2003089601-A2 3-DEOXYGLUCOSONE AND SKIN DYNAMIS THERAPEUTICS, INC. (US) 2003-10-30 WO claimed
US-20210179852-A1 Products by Upcycling Landfill Waste Streams NYSTROM KENNETH A (US) 2021-06-17 US disclosed
US-11034837-B2 Products by upcycling landfill waste streams NYSTROM KENNETH (US) 2021-06-15 US disclosed
US-20200362172-A1 Products by Upcycling Landfill Waste Streams NYSTROM KENNETH (US) 2020-11-19 US disclosed
US-10703909-B1 Products by upcycling landfill waste streams NYSTROM KENNETH (US) 2020-07-07 US disclosed
CN-105566997-A Waste paper deinking agent and preparation method and application thereof XUZHOU INST TECHNOLOGY 2016-05-11 CN disclosed
US-7868135-B2 Compositions of lipopeptide antibiotic derivatives and methods of use thereof BIOWEST THERAPEUTICS INC. (CA) 2011-01-11 US disclosed
EP-1175155-A1 METHOD FOR REDUCING A SUSCEPTIBILITY TO TUMOR FORMATION INDUCED BY 3-DEOXYGLUCOSONE AND PRECURSORS THEREOF FOX CHASE CANCER CENTER (US) 2002-01-30 EP disclosed
WO-2000062626-A1 METHOD FOR REDUCING A SUSCEPTIBILITY TO TUMOR FORMATION INDUCED BY 3-DEOXYGLUCOSONE AND PRECURSORS THEREOF FOX CHASE CANCER CENTER (US) 2000-10-26 WO disclosed
US-5514676-A TO INHIBIT THE FORMATION OF ADVANCED GLYCOSLYATION PRODUCTS BY THE NONENZYMATIC CROSSLINKING OF PROTEINS WITH REDUCING SUGARS, USED IN FOOD PRESERVATION AND TO PREVENT PROTEIN AGING IN COLLAGEN OR LENSES IN THE EYE PRESERVATION THE ROCKEFELLER UNIVERSITY (US) 1996-05-07 US disclosed
US-4338436-A ANTIBIOTICS ELI LILLY AND COMPANY (US) 1982-07-06 US disclosed
US-4338439-A BACTERICIDAL ANTIBIOTICS ELI LILLY AND COMPANY (US) 1982-07-06 US disclosed
US-4319028-A 7-(2-(Substituted benzoyl)amino)acetamido)cephalosporins ELI LILLY AND COMPANY (US) 1982-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070065443-A1 Fructoseamine 3 kinase and the formation of collagen and elastin FN3K, PDXK, COLGALT1 CA12 2753/4885CA1 1894/4885CA2 1243/4885
US-20030219440-A1 3-deoxyglucosone and skin DPM1, G6PD, UGGT1 CA12 2292/4885CA1 4084/4885CA2 1727/4885
US-20050159383-A1 Administering enzyme inhibitors; wrinkling and aging resistance; prevents formation Advanced Glycation End Products (AGEs) AGER, GLA, GALE CA12 4810/4885CA1 4767/4885CA2 2183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.