Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514556 | 0.76 | KMT2A (0.43) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL7519497 | 0.74 | KMT2A (1.00) | KMT2APKMNPC1MAPTMEN1 | |
| SCHEMBL7513811 | 0.73 | ITGA4 (0.51) | KMT2APKMALDH1A1 | |
| SCHEMBL7513160 | 0.71 | MYC (0.47) | KMT2AMAPTMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL23442159 | 0.68 | PRSS1 (0.62) | KMT2APKMNPC1RAB9AMAPT | |
| SCHEMBL7733774 | 0.68 | MAPT (0.55) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL7733778 | 0.68 | MAPT (0.55) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL8482486 | 0.68 | ALDH1A1 (0.62) | KMT2APKMMAPTMEN1SMN1; SMN2 | |
| SCHEMBL28571281 | 0.67 | NPC1 (0.43) | KMT2ANPC1RAB9AMAPTMEN1 | |
| SCHEMBL11280733 | 0.67 | KMT2A (0.56) | KMT2APKMNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032262-A1 | 2-aminoarylmethylamine solid support templated for preparation of highly functionalized heterocycle compounds | ZHANG JINFANG (US) | 2002-03-14 | — | — | US | disclosed |