SCHEMBL7513811

SCHEMBL7513811

COC(=O)[C@H](Cc1ccccc1)NCc1ccc(C(N)=O)cc1[N+](=O)[O-]

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ITGA4 P13612 7/20 0.51
ITGB7 P26010 7/20 0.51
PKM P14618 1/20 0.48
KMT2A Q03164 1/20 0.48
ALDH1A1 P00352 1/20 0.44
ATM Q13315 1/20 0.43
CTSD P07339 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6616257 0.85 ALDH1A1 (0.60) ITGA4ITGB7ALDH1A1ATM
SCHEMBL6616256 0.85 ALDH1A1 (0.60) ITGA4ITGB7ALDH1A1ATM
SCHEMBL7514782 0.84 LNPEP (0.52) ITGA4ITGB7ALDH1A1ATM
SCHEMBL7514776 0.84 LNPEP (0.52) ITGA4ITGB7ALDH1A1ATM
SCHEMBL7514551 0.76 LNPEP (0.53) ITGA4ITGB7ALDH1A1ATM
SCHEMBL7514543 0.76 LNPEP (0.53) ITGA4ITGB7ALDH1A1ATM
SCHEMBL6801977 0.74 ITGA4 (0.59) ITGA4ITGB7KMT2AATM
SCHEMBL6806963 0.74 ITGA4 (0.59) ITGA4ITGB7KMT2AATM
SCHEMBL7513823 0.73 KMT2A (0.59) PKMKMT2AALDH1A1
SCHEMBL3959739 0.73 ATM (0.68) ITGA4ITGB7KMT2AALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020032262-A1 2-aminoarylmethylamine solid support templated for preparation of highly functionalized heterocycle compounds ZHANG JINFANG (US) 2002-03-14 US disclosed