Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 16/20 | 0.71 |
| ▸ | TAS1R1 | Q7RTX1 | 16/20 | 0.71 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5464318 | 0.96 | TAS1R3 (0.66) | TAS1R3TAS1R1LNPEP | |
| SCHEMBL5464314 | 0.96 | TAS1R3 (0.66) | TAS1R3TAS1R1LNPEP | |
| SCHEMBL4197741 | 0.88 | TAS1R3 (0.74) | TAS1R3TAS1R1BCL2L1 | |
| SCHEMBL25496209 | 0.88 | TAS1R3 (0.74) | TAS1R3TAS1R1BCL2L1 | |
| SCHEMBL4197744 | 0.88 | TAS1R3 (0.74) | TAS1R3TAS1R1BCL2L1 | |
| SCHEMBL26814846 | 0.87 | TAS1R3 (0.69) | TAS1R3TAS1R1BCL2L1 | |
| SCHEMBL10407750 | 0.86 | TAS1R3 (0.68) | TAS1R3TAS1R1 | |
| SCHEMBL6241209 | 0.86 | TAS1R3 (0.68) | TAS1R3TAS1R1 | |
| SCHEMBL13885653 | 0.84 | LNPEP (0.56) | TAS1R3TAS1R1LNPEP | |
| SCHEMBL702469 | 0.84 | TAS1R3 (0.76) | TAS1R3TAS1R1BCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362165-B1 | Hydroxyphenyl derivatives with HIV integrase inhibitory properties | PHARMACOR INC. (CA) | 2002-03-26 | — | — | US | disclosed |
| EP-1165492-A1 | HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | Pharmacor Inc. (CA) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059867-A1 | HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | PHARMACOR INC. (CA) | 2000-10-12 | — | — | WO | disclosed |