SCHEMBL7513873

SCHEMBL7513873

COc1ccc2cc(CBr)c(=O)oc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR55 Q9Y2T6 2/20 0.67
CYP19A1 P11511 1/20 0.58
ALDH1A1 P00352 5/20 0.57
MAOB P27338 5/20 0.57
HPGD P15428 4/20 0.57
GAA P10253 4/20 0.57
GLA P06280 4/20 0.57
SLC16A3 O15427 1/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
CA12 O43570 3/20 0.56
CA9 Q16790 3/20 0.56
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
KDM4E B2RXH2 5/20 0.55
CA3 P07451 2/20 0.55
CA4 P22748 2/20 0.55
CA6 P23280 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12523188 0.88 GPR55 (0.70) GPR55CYP19A1ALDH1A1MAOBHPGD
SCHEMBL11618512 0.85 GPR55 (0.67) GPR55CYP19A1ALDH1A1MAOBHPGD
SCHEMBL6996805 0.84 GLA (0.62) GPR55ALDH1A1MAOBHPGDGAA
SCHEMBL27221219 0.82 GPR55 (0.64) GPR55CYP19A1ALDH1A1MAOBHPGD
SCHEMBL21121524 0.81 GPR55 (0.66) GPR55CYP19A1ALDH1A1MAOBHPGD
SCHEMBL2689001 0.81 GPR55 (0.62) GPR55CYP19A1ALDH1A1MAOBHPGD
SCHEMBL1284982 0.81 GPR55 (0.62) GPR55CYP19A1ALDH1A1MAOBHPGD
SCHEMBL28509670 0.81 KDM4E (0.53) GPR55ALDH1A1MAOBHPGDGAA
SCHEMBL5464496 0.80 GPR55 (0.61) GPR55CYP19A1ALDH1A1MAOBHPGD
SCHEMBL4282429 0.80 MCL1 (0.49) GPR55MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340027-A1 UBIQUITIN HIGH AFFINITY PEPTIDES, AND METHODS OF USING SAME, AND IDENTIFYING SAME TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2023-10-26 US disclosed
CN-112345664-A Method for measuring residual quantity of perfluorocarboxylic acids in animal-derived food 湖北省产品质量监督检验研究院 2021-02-09 CN disclosed
CN-110218207-B Coumarin hybrid pyridone compound with iron chelation and monoamine oxidase B inhibition activity and preparation and application thereof 浙江工业大学 2020-12-25 CN disclosed
EP-2813891-B1 Photoresist underlayer film-forming composition and pattern forming process SHINETSU CHEMICAL CO (JP) 2018-01-17 EP disclosed
US-9620363-B2 Underlayer film-forming composition and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-04-11 US disclosed
US-9620363-B2 Underlayer film-forming composition and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-04-11 US disclosed
EP-2813891-A2 Photoresist underlayer film-forming composition and pattern forming process Shin-Etsu Chemical Co., Ltd. (JP) 2014-12-17 EP disclosed
US-20140363956-A1 UNDERLAYER FILM-FORMING COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-12-11 US disclosed
US-20140363956-A1 UNDERLAYER FILM-FORMING COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-12-11 US disclosed
EP-1119554-A4 XANTHAN-ESTER AND ACRIDAN SUBSTRATES FOR HORSERADISH PEROXIDASE TROPIX INC (US) 2002-05-08 EP disclosed
EP-1119554-A1 XANTHAN-ESTER AND ACRIDAN SUBSTRATES FOR HORSERADISH PEROXIDASE TROPIX, INC. (US) 2001-08-01 EP disclosed
WO-2000015618-A1 XANTHAN-ESTER AND ACRIDAN SUBSTRATES FOR HORSERADISH PEROXIDASE TROPIX, INC. (US) 2000-03-23 WO disclosed