Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | MAOB | P27338 | 4/20 | 0.57 |
| ▸ | GLA | P06280 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA3 | P07451 | 2/20 | 0.57 |
| ▸ | CA4 | P22748 | 2/20 | 0.57 |
| ▸ | CA6 | P23280 | 2/20 | 0.57 |
| ▸ | CA7 | P43166 | 2/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.53 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.53 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12523188 | 0.87 | GPR55 (0.70) | GPR55ALDH1A1KDM4EHPGDMAOB | |
| SCHEMBL1284980 | 0.82 | MAOB (0.64) | GPR55MAOBCA12CA9CA2 | |
| SCHEMBL7513873 | 0.81 | GPR55 (0.67) | GPR55ALDH1A1KDM4EHPGDMAOB | |
| SCHEMBL11618512 | 0.81 | GPR55 (0.67) | GPR55ALDH1A1KDM4EHPGDMAOB | |
| SCHEMBL1284769 | 0.80 | MAOB (0.57) | ALDH1A1KDM4EHPGDMAOBCA12 | |
| SCHEMBL27221219 | 0.79 | GPR55 (0.64) | GPR55ALDH1A1KDM4EHPGDMAOB | |
| SCHEMBL2689001 | 0.78 | GPR55 (0.62) | GPR55ALDH1A1KDM4EHPGDMAOB | |
| SCHEMBL21121524 | 0.78 | GPR55 (0.66) | GPR55ALDH1A1KDM4EHPGDMAOB | |
| SCHEMBL5464496 | 0.77 | GPR55 (0.61) | GPR55ALDH1A1KDM4EHPGDMAOB | |
| SCHEMBL1284893 | 0.76 | NPC1 (0.57) | GPR55ALDH1A1KDM4EHPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383843-B2 | Method for preparing a coumarin compound, chromene compound, and method for preparing a chromene compound | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-02-26 | — | — | US | disclosed |
| US-20120088923-A1 | METHOD FOR PREPARING A COUMARIN COMPOUND, CHROMENE COMPOUND, AND METHOD FOR PREPARING A CHROMENE COMPOUND | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088923-A1 | METHOD FOR PREPARING A COUMARIN COMPOUND, CHROMENE COMPOUND, AND METHOD FOR PREPARING A CHROMENE COMPOUND | CYP3A7, CYP2A7, F7 | GPR55 2631/4885ALDH1A1 943/4885KDM4E 3026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.