Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24774791 | 0.79 | KDM4E (0.44) | KDM4EMAPTTP53POLBALDH1A1 | |
| SCHEMBL29922149 | 0.79 | KDM4E (0.44) | KDM4EMAPTTP53POLBALDH1A1 | |
| SCHEMBL11780453 | 0.74 | KDM4E (0.61) | KDM4EHTTMAPTHSD17B10TP53 | |
| SCHEMBL29368738 | 0.72 | KDM4E (0.63) | KDM4EHTTMAPTHSD17B10TP53 | |
| SCHEMBL6907648 | 0.72 | KDM4E (0.63) | KDM4EHTTMAPTHSD17B10TP53 | |
| SCHEMBL9643280 | 0.69 | ABCB11 (0.64) | KDM4EHTTMAPTHSD17B10TP53 | |
| SCHEMBL9642040 | 0.68 | ABCB11 (0.62) | KDM4EHTTMAPTHSD17B10TP53 | |
| SCHEMBL9713872 | 0.68 | KDM4E (0.59) | KDM4EHTTMAPTHSD17B10TP53 | |
| SCHEMBL13666895 | 0.67 | KDM4E (0.62) | KDM4EHTTMAPTHSD17B10TP53 | |
| SCHEMBL4236124 | 0.67 | HTT (0.40) | KDM4EHTTMAPTHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498182-B2 | BENZO(G)INDOLE -2,5(3H)-DIONE AND -2-ONE DERIVATIVE ANTIDIABETIC AGENTS | BIOVITRUM AB (SE) | 2002-12-24 | — | — | US | claimed |
| US-20020061921-A1 | Novel compounds | BIOVITRUM AB (SE) | 2002-05-23 | — | — | US | claimed |
| WO-2002026707-A1 | NOVEL COMPOUNDS | BIOVITRUM AB (SE) | 2002-04-04 | — | — | WO | claimed |
| US-6498182-B2 | BENZO(G)INDOLE -2,5(3H)-DIONE AND -2-ONE DERIVATIVE ANTIDIABETIC AGENTS | BIOVITRUM AB (SE) | 2002-12-24 | — | — | US | disclosed |
| US-20020061921-A1 | Novel compounds | BIOVITRUM AB (SE) | 2002-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061921-A1 | Novel compounds | GPR119, IAPP, GLP1R | KDM4E 3099/4885HTT 4679/4885MAPT 4596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.