Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.33 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24774791 | 1.00 | KDM4E (0.44) | KDM4EALDH1A1SMN1; SMN2MAPK1PDK2 | |
| SCHEMBL7513878 | 0.79 | KDM4E (0.42) | KDM4EALDH1A1SMN1; SMN2MAPK1PDK2 | |
| SCHEMBL12809947 | 0.74 | ALDH1A1 (0.42) | KDM4EALDH1A1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL29922289 | 0.69 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL24774081 | 0.69 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL13067358 | 0.68 | ALDH1A1 (0.41) | KDM4EALDH1A1SMN1; SMN2MAPK1PDK2 | |
| SCHEMBL757747 | 0.67 | KDM4E (0.82) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL8859782 | 0.67 | ALDH1A1 (0.82) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL52405 | 0.65 | ALDH1A1 (1.00) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 | |
| SCHEMBL29366129 | 0.65 | ALDH1A1 (1.00) | KDM4EALDH1A1SMN1; SMN2MAPK1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4054560-A1 | RIG-I INNATE IMMUNE RECEPTOR ANTAGONISTS AND METHODS OF USING SAME | Yale University (US) | 2022-09-14 | — | — | EP | disclosed |