Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.61 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.61 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5193579 | 0.86 | GABRA1 (0.56) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL4965511 | 0.84 | GABRA1 (0.56) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL12786969 | 0.83 | GABRA1 (0.69) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL3720055 | 0.82 | GABRA1 (0.67) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL7511784 | 0.82 | KDM4E (0.48) | MEN1KMT2AALDH1A1TP53HPGD | |
| SCHEMBL10519075 | 0.81 | GABRA1 (0.66) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL2909775 | 0.80 | GABRA1 (0.65) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL2910577 | 0.80 | GABRA1 (0.65) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL13930267 | 0.80 | GABRA1 (0.67) | GABRA1GABRB2GABRB1GABRA3MEN1 | |
| SCHEMBL17242463 | 0.79 | GABRA1 (0.66) | GABRA1GABRB2GABRB1GABRA3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226146-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001032655-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2001-05-10 | — | — | WO | disclosed |