Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5303665 | 0.84 | KDM4E (0.48) | KDM4EHPGDALDH1A1CYP1A2MEN1 | |
| SCHEMBL7514224 | 0.82 | GABRA1 (0.61) | KDM4EHPGDALDH1A1CYP1A2MEN1 | |
| SCHEMBL4962381 | 0.81 | KDM4E (0.48) | KDM4EHPGDALDH1A1CYP1A2MEN1 | |
| SCHEMBL1421967 | 0.81 | KDM4E (0.55) | KDM4EHPGDALDH1A1CYP1A2MEN1 | |
| SCHEMBL631845 | 0.79 | KDM4E (0.52) | KDM4EHPGDALDH1A1CYP1A2MEN1 | |
| SCHEMBL12786970 | 0.77 | KDM4E (0.52) | KDM4EHPGDALDH1A1CYP1A2MEN1 | |
| SCHEMBL6714523 | 0.77 | HPGD (0.45) | KDM4EHPGDALDH1A1CYP1A2MEN1 | |
| SCHEMBL9319718 | 0.75 | KDM4E (0.59) | KDM4EHPGDALDH1A1CYP1A2MEN1 | |
| SCHEMBL17242475 | 0.74 | KDM4E (0.60) | KDM4EHPGDALDH1A1CYP1A2MEN1 | |
| SCHEMBL5191098 | 0.73 | HTT (0.42) | KDM4EHPGDALDH1A1PRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226146-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001032655-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2001-05-10 | — | — | WO | disclosed |