SCHEMBL7514231

SCHEMBL7514231

Clc1ccc(N=NC(=NNc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.68
RAB9A P51151 5/20 0.68
NPC1 O15118 3/20 0.68
MAPT P10636 9/20 0.50
HTT P42858 7/20 0.50
GAA P10253 6/20 0.50
TDP1 Q9NUW8 6/20 0.50
MAPK1 P28482 3/20 0.50
KDM4E B2RXH2 2/20 0.50
HSP90AA1 P07900 2/20 0.50
ALDH1A1 P00352 6/20 0.46
LMNA P02545 3/20 0.46
SMN1; SMN2 Q16637 6/20 0.45
ALOX12 P18054 3/20 0.45
NPSR1 Q6W5P4 2/20 0.45
NPY1R P25929 1/20 0.45
NPY2R P49146 1/20 0.45
KMT2A Q03164 7/20 0.44
MEN1 O00255 6/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7514226 0.94 L3MBTL1 (0.68) L3MBTL1RAB9ANPC1MAPTHTT
SCHEMBL7507720 0.94 L3MBTL1 (0.68) L3MBTL1RAB9ANPC1MAPTHTT
SCHEMBL3889602 0.94 L3MBTL1 (0.63) L3MBTL1RAB9ANPC1MAPTHTT
SCHEMBL491429 0.89 RAB9A (0.73) L3MBTL1RAB9ANPC1MAPTHTT
SCHEMBL322062 0.89 RAB9A (0.73) L3MBTL1RAB9ANPC1MAPTHTT
SCHEMBL29812424 0.88 RAB9A (0.71) L3MBTL1RAB9ANPC1MAPTHTT
SCHEMBL3880196 0.86 RAB9A (0.69) L3MBTL1RAB9ANPC1MAPTHTT
SCHEMBL11421680 0.85 RAB9A (0.68) L3MBTL1RAB9ANPC1MAPTHTT
SCHEMBL3895198 0.85 RAB9A (0.68) L3MBTL1RAB9ANPC1MAPTHTT
SCHEMBL3888821 0.82 RAB9A (0.64) L3MBTL1RAB9ANPC1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4143049-A METHOD FOR PREPARING 2H-TETRAZOLIUM CHLORIDE AND 2H-TETRAZOLIUM CHLORIDE HYDROCHLORIDE OSTROVSKAYA VERA M 1979-03-06 US claimed
JP-62299864-A None JP disclosed
US-6455210-B1 SUPPORT, PHOTOTHERMOGRAPHIC IMAGE- RECEIVING LAYERS, AND ANTIHALATION LAYER OR FILTER LAYERS OF A DYE AND A HEXAARYLBIIMIDAZOLE IN A DISPERSION OF A HYDROPHILIC POLYMER EASTMAN KODAK COMPANY 2002-09-24 US disclosed
US-20020106590-A1 AQUEOUS THERMALLY BEACHABLE COMPOSITION USEFUL IN A PHOTOTHERMOGRAPHIC ELEMENT CARESTREAM HEALTH, INC. 2002-08-08 US disclosed
EP-1217431-A2 An aqueous thermally bleachable composition useful in a photothermographic element EASTMAN KODAK COMPANY (US) 2002-06-26 EP disclosed
JP-S62299864-A ELECTROPHOTOGRAPHIC LITHOGRAPHIC PLATE MATERIAL RICOH CO LTD 1987-12-26 JP disclosed
US-4201590-A Heat sensitive reactive products of hexaarylbiimidazole and antihalation dyes EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4196002-A HEXAARYLBISMIIDAZOLE, COLORLESS EASTMAN KODAK COMPANY (US) 1980-04-01 US disclosed
US-4143049-A METHOD FOR PREPARING 2H-TETRAZOLIUM CHLORIDE AND 2H-TETRAZOLIUM CHLORIDE HYDROCHLORIDE OSTROVSKAYA VERA M 1979-03-06 US disclosed