SCHEMBL491429

SCHEMBL491429

c1ccc(/N=N/C(=N/Nc2ccccc2)c2ccccc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.73
L3MBTL1 Q9Y468 4/20 0.73
NPC1 O15118 4/20 0.73
TDP1 Q9NUW8 6/20 0.56
GAA P10253 6/20 0.56
MAPT P10636 4/20 0.56
HTT P42858 4/20 0.56
MAPK1 P28482 3/20 0.56
KDM4E B2RXH2 3/20 0.56
HSP90AA1 P07900 1/20 0.56
ALDH1A1 P00352 4/20 0.55
LMNA P02545 2/20 0.55
CYP1A1 P04798 1/20 0.50
TSHR P16473 1/20 0.50
CYP1B1 Q16678 1/20 0.50
KMT2A Q03164 5/20 0.49
SMN1; SMN2 Q16637 4/20 0.49
MEN1 O00255 3/20 0.49
POLB P06746 1/20 0.49
PKM P14618 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL322062 1.00 RAB9A (0.73) RAB9AL3MBTL1NPC1TDP1GAA
SCHEMBL29812424 0.92 RAB9A (0.71) RAB9AL3MBTL1NPC1TDP1GAA
SCHEMBL3880196 0.90 RAB9A (0.69) RAB9AL3MBTL1NPC1TDP1GAA
SCHEMBL3881493 0.90 RAB9A (0.65) RAB9AL3MBTL1NPC1TDP1GAA
SCHEMBL11421677 0.89 RAB9A (0.68) RAB9AL3MBTL1NPC1TDP1GAA
SCHEMBL7514231 0.89 L3MBTL1 (0.68) RAB9AL3MBTL1NPC1TDP1GAA
SCHEMBL3895200 0.89 RAB9A (0.68) RAB9AL3MBTL1NPC1TDP1GAA
SCHEMBL11421680 0.89 RAB9A (0.68) RAB9AL3MBTL1NPC1TDP1GAA
SCHEMBL11421678 0.89 RAB9A (0.68) RAB9AL3MBTL1NPC1TDP1GAA
SCHEMBL7514226 0.89 L3MBTL1 (0.68) RAB9AL3MBTL1NPC1TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4143049-A METHOD FOR PREPARING 2H-TETRAZOLIUM CHLORIDE AND 2H-TETRAZOLIUM CHLORIDE HYDROCHLORIDE OSTROVSKAYA VERA M 1979-03-06 US claimed
US-3990947-A Composition for detecting fibrinogen, fibrinogen split products and fibrin split products WARNER-LAMBERT COMPANY (US) 1976-11-09 US claimed
US-12600800-B2 Therapeutic use of mitochondria and combined mitochondrial agents CHILDREN'S MEDICAL CENTER CORPORATION (US) 2026-04-14 US disclosed
US-12599429-B2 Methods for controlling treatment volumes, thermal gradients, muscle stimulation, and immune responses in pulsed electric field treatments NORTH CAROLINA STATE UNIVERSITY (US) 2026-04-14 US disclosed
US-20260041481-A1 METHODS FOR CONTROLLING TREATMENT VOLUMES, THERMAL GRADIENTS, MUSCLE STIMULATION, AND IMMUNE RESPONSES IN PULSED ELECTRIC FIELD TREATMENTS UNIV NORTH CAROLINA STATE (US) 2026-02-12 US disclosed
US-20260014293-A1 HEMOSTATIC AGENT IN PASTE FORM, USE THEREOF, AND METHOD FOR PRODUCING A LOCAL ACTIVE AGENT RELEASE SYSTEM HERAEUS MEDICAL GMBH (DE) 2026-01-15 US disclosed
EP-4678196-A1 PASTY HAEMOSTYPTIC, ITS USE AND A METHOD FOR THE PREPARATION OF A LOCAL DRUG DELIVERY SYSTEM Heraeus Medical GmbH (DE) 2026-01-14 EP disclosed
EP-4653048-A2 THERAPEUTIC USE OF MITOCHONDRIA AND COMBINED MITOCHONDRIAL AGENTS The Children's Medical Center Corporation (US) 2025-11-26 EP disclosed
EP-4272834-B1 THERAPEUTIC USE OF MITOCHONDRIA AND COMBINED MITOCHONDRIAL AGENTS CHILDRENS MEDICAL CT CORP (US) 2025-09-03 EP disclosed
US-20250019650-A1 NEURAL CELL EXTRACELLULAR VESICLES ARUNA BIO, INC. (US) 2025-01-16 US disclosed
US-12168700-B2 Therapeutic use of mitochondria and combined mitochondrial agents CHILDREN'S MEDICAL CENTER CORPORATION (US) 2024-12-17 US disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
US-6455210-B1 SUPPORT, PHOTOTHERMOGRAPHIC IMAGE- RECEIVING LAYERS, AND ANTIHALATION LAYER OR FILTER LAYERS OF A DYE AND A HEXAARYLBIIMIDAZOLE IN A DISPERSION OF A HYDROPHILIC POLYMER EASTMAN KODAK COMPANY 2002-09-24 US disclosed
US-20020106590-A1 AQUEOUS THERMALLY BEACHABLE COMPOSITION USEFUL IN A PHOTOTHERMOGRAPHIC ELEMENT CARESTREAM HEALTH, INC. 2002-08-08 US disclosed
EP-1217431-A2 An aqueous thermally bleachable composition useful in a photothermographic element EASTMAN KODAK COMPANY (US) 2002-06-26 EP disclosed
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4201590-A Heat sensitive reactive products of hexaarylbiimidazole and antihalation dyes EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4196002-A HEXAARYLBISMIIDAZOLE, COLORLESS EASTMAN KODAK COMPANY (US) 1980-04-01 US disclosed
US-4143049-A METHOD FOR PREPARING 2H-TETRAZOLIUM CHLORIDE AND 2H-TETRAZOLIUM CHLORIDE HYDROCHLORIDE OSTROVSKAYA VERA M 1979-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260041481-A1 METHODS FOR CONTROLLING TREATMENT VOLUMES, THERMAL GRADIENTS, MUSCLE STIMULATION, AND IMMUNE RESPONSES IN PULSED ELECTRIC FIELD TREATMENTS TNNC1, TNNT2, MUSK RAB9A 2346/4885L3MBTL1 1476/4885NPC1 4184/4885
US-20260014293-A1 HEMOSTATIC AGENT IN PASTE FORM, USE THEREOF, AND METHOD FOR PRODUCING A LOCAL ACTIVE AGENT RELEASE SYSTEM F9, PLAT, F12 RAB9A 861/4885L3MBTL1 2310/4885NPC1 815/4885
US-12599429-B2 Methods for controlling treatment volumes, thermal gradients, muscle stimulation, and immune responses in pulsed electric field treatments TNNC1, TNNT2, TNNI3 RAB9A 3368/4885L3MBTL1 2977/4885NPC1 4671/4885
US-12600800-B2 Therapeutic use of mitochondria and combined mitochondrial agents FECH, UQCRC2, ATP5PD RAB9A 2257/4885L3MBTL1 1308/4885NPC1 1903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.