Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514473 | 1.00 | LNPEP (0.47) | LNPEPROCK2CA1CA2POLB | |
| SCHEMBL28217498 | 0.90 | LNPEP (0.58) | LNPEPROCK2CA1CA2POLB | |
| SCHEMBL28217499 | 0.90 | LNPEP (0.58) | LNPEPROCK2CA1CA2POLB | |
| SCHEMBL7703695 | 0.88 | LNPEP (0.53) | LNPEPROCK2CA1CA2POLB | |
| SCHEMBL6140530 | 0.78 | LCK (0.67) | LNPEPCA1CA2GAARAB9A | |
| SCHEMBL17486396 | 0.77 | LNPEP (0.52) | LNPEPROCK2CA1CA2POLB | |
| SCHEMBL24835066 | 0.77 | ACACB (0.47) | POLBMAPTTDP1ITGA4ITGB7 | |
| SCHEMBL19364232 | 0.77 | ACACB (0.48) | POLBMAPTTDP1ITGA4ITGB7 | |
| SCHEMBL19364226 | 0.76 | ACACB (0.47) | POLBMAPTTDP1ITGA4ITGB7 | |
| SCHEMBL22384242 | 0.76 | LNPEP (0.55) | LNPEPROCK2CA1CA2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362165-B1 | Hydroxyphenyl derivatives with HIV integrase inhibitory properties | PHARMACOR INC. (CA) | 2002-03-26 | — | — | US | disclosed |
| EP-1165492-A1 | HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | Pharmacor Inc. (CA) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000059867-A1 | HYDROXYPHENYL DERIVATIVES WITH HIV INTEGRASE INHIBITORY PROPERTIES | PHARMACOR INC. (CA) | 2000-10-12 | — | — | WO | disclosed |