Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.58 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28217498 | 1.00 | LNPEP (0.58) | LNPEPERAP2ERAP1CA1CA2 | |
| SCHEMBL7514473 | 0.90 | LNPEP (0.47) | LNPEPCA1CA2ROCK2POLB | |
| SCHEMBL7514478 | 0.90 | LNPEP (0.47) | LNPEPCA1CA2ROCK2POLB | |
| SCHEMBL22384242 | 0.86 | LNPEP (0.55) | LNPEPERAP2ERAP1CA1CA2 | |
| SCHEMBL15037126 | 0.86 | LNPEP (0.55) | LNPEPERAP2ERAP1CA1CA2 | |
| SCHEMBL27616693 | 0.84 | CTSL (0.60) | LNPEPLY96ROCK2CTSSCTSK | |
| SCHEMBL7703695 | 0.84 | LNPEP (0.53) | LNPEPERAP2ERAP1CA1CA2 | |
| SCHEMBL17486396 | 0.82 | LNPEP (0.52) | LNPEPERAP2ERAP1CA1CA2 | |
| SCHEMBL7516005 | 0.81 | CA2 (0.67) | LNPEPCA1CA2 | |
| SCHEMBL28217500 | 0.81 | CA2 (0.67) | LNPEPCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106045932-B | A kind of compound and its application with radiosensitizing effect | 浙江省肿瘤医院 | 2018-05-15 | — | — | CN | disclosed |