Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.48 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7514551 | 1.00 | LNPEP (0.53) | LNPEPITGA4ITGB7ERAP2ERAP1 | |
| SCHEMBL7514776 | 0.92 | LNPEP (0.52) | LNPEPITGA4ITGB7ERAP2ERAP1 | |
| SCHEMBL7514782 | 0.92 | LNPEP (0.52) | LNPEPITGA4ITGB7ERAP2ERAP1 | |
| SCHEMBL5075625 | 0.81 | ATM (0.59) | ITGA4ITGB7GAARAB9AMEP1B | |
| SCHEMBL2375646 | 0.78 | ATM (0.68) | ITGA4ITGB7GAARAB9AATM | |
| SCHEMBL2375644 | 0.78 | ATM (0.68) | ITGA4ITGB7GAARAB9AATM | |
| SCHEMBL3959739 | 0.78 | ATM (0.68) | ITGA4ITGB7GAARAB9AATM | |
| SCHEMBL7513005 | 0.77 | LNPEP (0.52) | LNPEPERAP2ERAP1GAARAB9A | |
| SCHEMBL7513015 | 0.77 | LNPEP (0.52) | LNPEPERAP2ERAP1GAARAB9A | |
| Hydrochloric Acid SCHEMBL17822192 | 0.77 | ATM (0.67) | ITGA4ITGB7GAARAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032262-A1 | 2-aminoarylmethylamine solid support templated for preparation of highly functionalized heterocycle compounds | ZHANG JINFANG (US) | 2002-03-14 | — | — | US | disclosed |