Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 7/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.49 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | IL1RN | P18510 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7513015 | 1.00 | LNPEP (0.52) | LNPEPERAP2ERAP1MEP1BMEN1 | |
| SCHEMBL7513151 | 0.83 | ITGA4 (0.46) | MEP1BALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7513158 | 0.83 | ITGA4 (0.46) | MEP1BALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7514543 | 0.77 | LNPEP (0.53) | LNPEPERAP2ERAP1MEP1BALDH1A1 | |
| SCHEMBL7514551 | 0.77 | LNPEP (0.53) | LNPEPERAP2ERAP1MEP1BALDH1A1 | |
| SCHEMBL27987067 | 0.76 | KDM4E (0.49) | MEP1BMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2136933 | 0.74 | ALDH1A1 (0.50) | ERAP2ERAP1ALDH1A1IL1RNTRPM8 | |
| SCHEMBL2138849 | 0.74 | ALDH1A1 (0.50) | ERAP2ERAP1ALDH1A1IL1RNTRPM8 | |
| SCHEMBL22004939 | 0.74 | ALDH1A1 (0.50) | ERAP2ERAP1ALDH1A1IL1RNTRPM8 | |
| SCHEMBL7513020 | 0.73 | LNPEP (0.41) | LNPEPERAP2ERAP1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020032262-A1 | 2-aminoarylmethylamine solid support templated for preparation of highly functionalized heterocycle compounds | ZHANG JINFANG (US) | 2002-03-14 | — | — | US | disclosed |