Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.77 |
| ▸ | CTSL | P07711 | 11/20 | 0.70 |
| ▸ | CTSS | P25774 | 8/20 | 0.70 |
| ▸ | CTSB | P07858 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535888 | 0.94 | CTSK (0.76) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7512878 | 0.89 | CTSL (0.65) | CTSKCTSLCTSSCTSB | |
| SCHEMBL21109664 | 0.85 | CTSK (0.72) | CTSKCTSLCTSSCTSB | |
| SCHEMBL21109395 | 0.83 | CTSK (0.68) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7513191 | 0.83 | CTSL (0.67) | CTSKCTSLCTSSCTSB | |
| SCHEMBL21110247 | 0.82 | CTSK (0.67) | CTSKCTSLCTSSCTSB | |
| SCHEMBL7513925 | 0.82 | MEN1 (0.55) | CTSK | |
| SCHEMBL7513937 | 0.82 | MEN1 (0.55) | CTSK | |
| SCHEMBL21109591 | 0.82 | CTSK (0.66) | CTSKCTSLCTSSCTSB | |
| SCHEMBL21110049 | 0.81 | CTSK (0.71) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641800-B1 | Lactol derivatives as inhibitors of cathepsin L | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-01-16 | — | — | EP | disclosed |
| US-5496834-A | PEPTIDE DERIVATIVES AS CATHEPSIN L INHIBITORS AND INHIBITORS OF BONE RESORPTION OR TREATMENT OF OSTEOPOROSIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0641800-A1 | Lactol derivatives as inhibiters of cathepsin L | Takeda Chemical Industries, Ltd. (JP) | 1995-03-08 | — | — | EP | disclosed |