Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.60 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.60 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.58 |
| ▸ | HTR3B | O95264 | 2/20 | 0.58 |
| ▸ | HTR3A | P46098 | 2/20 | 0.58 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.58 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.58 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.58 |
| ▸ | CFTR | P13569 | 8/20 | 0.55 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.49 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.49 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.49 |
| ▸ | CHRNG | P07510 | 1/20 | 0.49 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2052030 | 0.88 | NR4A2 (0.79) | NR4A2CREBBPHTR3EHTR3BHTR3A | |
| SCHEMBL29696613 | 0.88 | NR4A2 (0.79) | NR4A2CREBBPHTR3EHTR3BHTR3A | |
| SCHEMBL376662 | 0.84 | GABRA1 (0.69) | GABRA1GABRB2CFTRGABRB1GABRA3 | |
| SCHEMBL29475801 | 0.84 | GABRA1 (0.69) | GABRA1GABRB2CFTRGABRB1GABRA3 | |
| Hydrochloric Acid SCHEMBL30417898 | 0.82 | GABRA1 (0.67) | GABRA1GABRB2CFTRGABRB1GABRA3 | |
| Hydrochloric Acid SCHEMBL29008098 | 0.82 | GABRA1 (0.67) | GABRA1GABRB2CFTRGABRB1GABRA3 | |
| SCHEMBL28306489 | 0.81 | NR4A2 (0.56) | NR4A2CREBBPHTR3EHTR3BHTR3A | |
| SCHEMBL22704179 | 0.81 | GABRA1 (0.61) | NR4A2CREBBPGABRA1GABRB2CFTR | |
| SCHEMBL29551347 | 0.80 | CFTR (0.67) | NR4A2GABRA1GABRB2CFTRPBRM1 | |
| SCHEMBL377150 | 0.80 | CFTR (0.67) | NR4A2GABRA1GABRB2CFTRPBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226146-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2002-07-31 | — | — | EP | claimed |
| WO-2001032655-A2 | QUINOLINE AND NAPHTHYRIDINE CARBOXYLIC ACID ANTIBACTERIALS | ABBOTT LABORATORIES (US) | 2001-05-10 | — | — | WO | claimed |
| US-20140256694-A1 | STEROID ANTIBIOTIC CONJUGATES | ALLERGAN, INC. (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256694-A1 | STEROID ANTIBIOTIC CONJUGATES | CYP17A1, CYP21A2, HSD17B1 | NR4A2 1446/4885CREBBP 4116/4885HTR3E 3924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.